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- Table of Contents
Facts about Adenylate cyclase type 1.
May be involved in regulatory processes in the central nervous system. May play a role in memory and learning.
Human | |
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Gene Name: | ADCY1 |
Uniprot: | Q08828 |
Entrez: | 107 |
Belongs to: |
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adenylyl cyclase class-4/guanylyl cyclase family |
Adenylate cyclase type 1
Mass (kDA):
123.44 kDA
Human | |
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Location: | 7p12.3 |
Sequence: | 7; NC_000007.14 (45574140..45723116) |
Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Brain, retina and adrenal medulla.
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane raft. Expressed in the cytoplasm of supporting cells and hair cells of the cochlea vestibule, as well as to the cochlear hair cell nuclei and stereocilia.
PMID: 8314585 by Villacres E.C., et al. Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase.
PMID: 11549699 by Cote M., et al. Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.