Adenosine deaminase 2 Antibodies

AND ADA2 ELISA kits, Adenosine deaminase 2 Proteins

Many biological assays use antibodies to detect Adenosine deaminase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adenosine deaminase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adenosine deaminase 2 antibodies...

We validate the specificity of these antibodies to Adenosine deaminase 2 by testing them on tissues known to express ADA2 positively and negatively. Browse below to find the ADA2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADA2 Infographic by Boster Bio

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Human CECR1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ9NZK5
Starting from 10ug

ADA2 Overview

Facts about Adenosine deaminase 2.

ADA2 3D structure. Source: alphafold

Adenosine deaminase 2 (ADA2)

Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity.

Binds to cell surfaces through proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. .

Gene Information

Human
Gene Name:	ADA2
Uniprot:	Q9NZK5
Entrez:	51816

Family

Belongs to:

metallo-dependent hydrolases superfamily

Alternative Names

Adenosine deaminase 2

Molecular Weight

Mass (kDA):
58.934 kDA

Genomic Context


Human

Location:	22q11.1
Sequence:	22; NC_000022.11 (17178790..17221854, complement)

Tissue Specificity

Detected in blood plasma (at protein level). Widely expressed, with most abundant expression in human adult heart, lung, lymphoblasts, and placenta as well as fetal lung, liver, and kidney. In embryo, expressed in the outflow tract and atrium of the developing heart, the VII/VIII cranial nerve ganglion, and the notochord.

Subcellular Localizations

Secreted.

Diseases

Vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome (VAIHS)

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADA2

References

PMID: 10756095 by Riazi M.A., et al. The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome.

PMID: 15926889 by Zavialov A.V., et al. Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity.