Alpha-actinin-3 Antibodies

AND ACTN3 ELISA kits, Alpha-actinin-3 Proteins

Many biological assays use antibodies to detect Alpha-actinin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-actinin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-actinin-3 antibodies...

We validate the specificity of these antibodies to Alpha-actinin-3 by testing them on tissues known to express ACTN3 positively and negatively. Browse below to find the ACTN3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: A1BG Next: ACVR1

ACTN3 Infographic by Boster Bio

All ACTN3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ACTN3 Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # PB10026
100 μg/vial

Anti-Human ACTN3 DyLight® 488 conjugated Antibody

Human

Flow Cytometry

$515
Cat # A02693-Dyl488
100 μg/vial

Anti-ACTN3 Antibody Picoband® (monoclonal, 9B5)

Mouse, Rat

IHC, WB

$370
Cat # M02693
100 μg/vial

Anti-Human ACTN3 DyLight® 550 conjugated Antibody

4 Q&As

Human

Flow Cytometry

$515
Cat # A02693-Dyl550
100 μg/vial

Anti-ACTN3 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M02693-1
100 μl/vial

ACTN3 (NM_001104) Human Over-expression Lysate

Human

$960
Cat # LS000089
100 µg

ACTN3 Overview

Facts about Alpha-actinin-3.

ACTN3 3D structure. Source: alphafold

Alpha-actinin-3 (ACTN3)

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Gene Information

Human
Gene Name:	ACTN3
Uniprot:	Q08043
Entrez:	89

Family

Belongs to:

alpha-actinin family

Alternative Names

actinin, alpha 3; Alpha-actinin skeletal muscle isoform 3; alpha-actinin skeletal muscle; alpha-actinin-3; F-actin cross-linking protein; MGC117002; MGC117005

Molecular Weight

Mass (kDA):
103.241 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (66546395..66563334)

Tissue Specificity

Expressed only in a subset of type 2 skeletal muscle fibers.

Diseases

Myopathy
Pain
Muscle Twitch
Neuromuscular Diseases
Glycogen Storage Disease Type V
Muscle Weakness
Fracture
Muscular Dystrophy
Cholangiocarcinoma
Coronary Microvascular Disease
Diabetes Mellitus
Dystrophy

Osteoporotic Fractures
Polymyositis
Myositis
Tissue Adhesions
Congenital Muscular Dystrophy (disorder)
Spinal Cord Injuries
Parathyroid Neoplasms

Interacting Proteins

ACTN1

Pathways

Cell Adhesion
Aging
Muscle Contraction
Cell Proliferation
Regulation Of Cell Adhesion
Cell Development
Response To Hypoxia
Neurogenesis
Metaphase
Oxidative Phosphorylation
Muscle Atrophy
Spermatogenesis

Cell Maturation
Regeneration
Germ Cell Development
Swimming
Cell Motility
Cell Differentiation
Meiosis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTN3

References

PMID: 1339456 by Beggs A.H., et al. Cloning and characterization of two human skeletal muscle alpha- actinin genes located on chromosomes 1 and 11.

PMID: 11440986 by Mills M., et al. Differential expression of the actin-binding proteins, alpha-actinin- 2 and -3, in different species: implications for the evolution of functional redundancy.

1 Publications of Boster Alpha-actinin-3 Antibodies & ELISA Kits

PubMed ID: 10.1186/s13395-021-00279-0, Protein profile of fiber types in human skeletal muscle: a single-fiber proteomi...

*More publications can be found for each product on its corresponding product page