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AARS1 Antibodies

AND AARS1 ELISA kits, AARS1 Proteins

Many biological assays use antibodies to detect AARS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AARS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AARS1 antibodies...

We validate the specificity of these antibodies to AARS1 by testing them on tissues known to express AARS1 positively and negatively. Browse below to find the AARS1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AARS1 Infographic by Boster Bio

AARS1 protein infographic

All AARS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-AlaRS/AARS1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03935-1
100 μg/vial

AlaRS (AARS) (NM_001605) Human Over-expression Lysate

Human

$628
Cat # LS000016
100 µg

AARS1 Overview

Facts about Alanine--tRNA ligase, cytoplasmic.

AARS1 3D structure

AARS1 3D structure. Source: alphafold

Alanine--tRNA ligase, cytoplasmic (AARS1)

Catalyzes the attachment of alanine into tRNA(Ala) in a two-step response: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala) (PubMed:27622773, PubMed:27911835, PubMed:28493438). Additionally edits incorrectly charged tRNA(Ala) via its editing domain (PubMed:27622773, PubMed:27911835, PubMed:28493438).

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Gene Information

Human
Gene Name:	AARS1
Uniprot:	P49588
Entrez:	16

Gene Information

Family

Belongs to:

class-II aminoacyl-tRNA synthetase family

Family

Alternative Names

Alanine--tRNA ligase, cytoplasmic

Molecular Weight

Mass (kDA):
106.81 kDA

Molecular Weight

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (70252295..70289509, complement)

Subcellular Localizations

Cytoplasm.

Subcellular Localization

Diseases

Charcot-Marie-Tooth disease 2N (CMT2N)

Disease

PTMs

Acetylation

Phosphoprotein

Ubl conjugation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AARS1

References

PMID: 7654687 by Shiba K., et al. Human alanyl-tRNA synthetase: conservation in evolution of catalytic core and microhelix recognition.

PMID: 16139798 by Giannakopoulos N.V., et al. Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.