AP2A2 Antibodies

AND AP2A2 ELISA kits, AP2A2 Proteins

Many biological assays use antibodies to detect AP2A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP2A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP2A2 antibodies...

We validate the specificity of these antibodies to AP2A2 by testing them on tissues known to express AP2A2 positively and negatively. Browse below to find the AP2A2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: A1BG Next: AP1B1

AP2A2 Infographic by Boster Bio

All AP2A2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-AP-2 complex subunit alpha-2 AP2A2 Antibody

Human, Mouse

$405
Cat # A08527
100ul

Anti-AP2A2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08527-1
100 μg/vial

alpha Adaptin (AP2A2) (NM_012305) Human Over-expression Lysate

Human

$628
Cat # LS000161
100 µg

AP2A2 Overview

Facts about AP-2 complex subunit alpha-2.

AP2A2 3D structure. Source: alphafold

AP-2 complex subunit alpha-2 (AP2A2)

Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways.

Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome.

Gene Information

Human
Gene Name:	AP2A2
Uniprot:	O94973
Entrez:	161

Family

Belongs to:

adaptor complexes large subunit family

Alternative Names

100 kDa coated vesicle protein C; Adapter-related protein complex 2 alpha-2 subunit; adaptin, alpha B; Adaptor protein complex AP-2 subunit alpha-2; adaptor-related protein complex 2, alpha 2 subunit; alpha2-adaptin; Alpha-adaptin C; alpha-adaptin C; Huntingtin interacting protein J; AP-2 complex subunit alpha-2; Clathrin assembly protein complex 2 alpha-C large chain; clathrin-associated/assembly/adaptor protein, large, alpha 2; DKFZP564D1864; HIP9ADTAB; Huntingtin yeast partner J; Huntingtin-interacting protein 9; Huntingtin-interacting protein J; HYPJCLAPA2; KIAA0899HIP-9; Plasma membrane a

Molecular Weight

Mass (kDA):
103.96 kDA

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (925809..1012245)

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.

Diseases

Wolff-parkinson-white Syndrome
Leukemia
Accessory Atrioventricular Bundle (disorder)

Interacting Proteins

Dab2
Kcnj11

Pathways

Cell Division
Asymmetric Cell Division
Cellular Process
Cytokinesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP2A2

References

PMID: 9700202 by Faber P.W., et al. Huntingtin interacts with a family of WW domain proteins.

PMID: 11532990 by Waelter S., et al. The huntingtin interacting protein HIP1 is a clathrin and alpha- adaptin-binding protein involved in receptor-mediated endocytosis.