ABCA3 Antibodies

AND ABCA3 ELISA kits, ABCA3 Proteins

Many biological assays use antibodies to detect ABCA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCA3 antibodies...

We validate the specificity of these antibodies to ABCA3 by testing them on tissues known to express ABCA3 positively and negatively. Browse below to find the ABCA3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABCA3 Infographic by Boster Bio

All ABCA3 Products

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Product

Figures

Specificity

Applications

Price

Anti-ABCA3 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A03086
100ul

ATP binding cassette sub family A member 3 (ABCA3) (NM_001089) Human Over-expression Lysate

Human

$960
Cat # LS000021
100 µg

ABCA3 Overview

Facts about ATP-binding cassette sub-family A member 3.

ABCA3 3D structure. Source: alphafold

ATP-binding cassette sub-family A member 3 (ABCA3)

Plays an essential part in the formation of pulmonary surfactant, likely by transporting lipids like cholesterol. .

Gene Information

Human
Gene Name:	ABCA3
Uniprot:	Q99758
Entrez:	21

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ABC transporter 3; ABC3MGC72201; ABC-C transporter; ABC-C; ATP-binding cassette 3; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette, sub-family A (ABC1), member 3; EC 3.6.3; EC 3.6.3.17; EST111653; LBM180; MGC166979; SMDP3

Molecular Weight

Mass (kDA):
191.362 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (2275881..2340728, complement)

Tissue Specificity

Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Lung Diseases
Pulmonary Fibrosis
Respiratory Distress Syndrome, Newborn
Respiratory Distress
Respiratory Failure
Lung Diseases, Interstitial
Pneumonia
Malignant Neoplasms
Hereditary Diseases
Pneumonia, Interstitial
Leukemia

Respiration Disorders
Fibrosis
Chronic Lung Disease
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Pulmonary Alveolar Proteinosis

Pathways

Transport
Surfactant Homeostasis
Lipid Transport
Secretion
Pathogenesis
Localization
Drug Resistance
Lipid Homeostasis
Exocytosis
Transmembrane Transport
Lung Development
Cell Proliferation
Cell Death

Drug Transport
Sterol Transport
Glycosylation
Membrane Fusion
Keratinization
Regulation Of Lipid Transport
Lung Morphogenesis

PTMs

Phosphorylation
Glycosylation

Cleavage
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCA3

References

PMID: 8706931 by Klugbauer N., et al. Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein.

PMID: 9027511 by Connors T.D., et al. The cloning of a human ABC gene (ABC3) mapping to chromosome 16p13.3.