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- Table of Contents
Facts about Multidrug resistance-associated protein 6.
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Human | |
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Gene Name: | ABCC6 |
Uniprot: | O95255 |
Entrez: | 368 |
Belongs to: |
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ABC transporter superfamily |
Anthracycline resistance-associated protein; ARAPXE; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; EST349056; MLP1ABC34; MOATE; MOAT-E; MRP6ATP-binding cassette sub-family C member 6; multidrug resistance-associated protein 6; Multi-specific organic anion transporter E; pseudoxanthoma elasticum; PXE1; URG7
Mass (kDA):
164.906 kDA
Human | |
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Location: | 16p13.11 |
Sequence: | 16; NC_000016.10 (16149565..16223617, complement) |
Expressed in kidney and liver. Very low expression in other tissues.
[Isoform 1]: Basolateral cell membrane; Multi-pass membrane protein.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein.
PMID: 10424734 by Belinsky M.G., et al. MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver.
PMID: 9892204 by Kool M., et al. Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells.