ADAM30 Antibodies

AND ADAM30 ELISA kits, ADAM30 Proteins

Many biological assays use antibodies to detect ADAM30, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAM30 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAM30 antibodies...

We validate the specificity of these antibodies to ADAM30 by testing them on tissues known to express ADAM30 positively and negatively. Browse below to find the ADAM30 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADAM30 Infographic by Boster Bio

All ADAM30 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ADA30 ADAM30 Antibody

Human

ELISA, WB

$380
Cat # A11894
100ul

ADAM30 (NM_021794) Human Over-expression Lysate

Human

$628
Cat # LS011085
100 µg

ADAM30 Overview

Facts about Disintegrin and metalloproteinase domain-containing protein 30.

ADAM30 3D structure. Source: alphafold

Disintegrin and metalloproteinase domain-containing protein 30 (ADAM30)

Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation (PubMed:27333034). .

Gene Information

Human
Gene Name:	ADAM30
Uniprot:	Q9UKF2
Entrez:	11085

Family

Belongs to:

No superfamily

Alternative Names

a disintegrin and metalloproteinase domain 30; ADAM 30; ADAM metallopeptidase domain 30; disintegrin and metalloproteinase domain-containing protein 30; EC 3.4.24.-; svph4

Molecular Weight

Mass (kDA):
88.94 kDA

Genomic Context


Human

Location:	1p12
Sequence:	1; NC_000001.11 (119893533..119896515, complement)

Tissue Specificity

Expressed in brain neurons (at protein level) (PubMed:27333034). Expressed in testis (PubMed:10512762).

Subcellular Localizations

Late endosome membrane; Single-pass type I membrane protein.

Diseases

Diabetes Mellitus, Non-insulin-dependent
Diabetes Mellitus

PTMs

Disulfide bond

Glycoprotein

Zymogen

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAM30

References

PMID: 10512762 by Cerretti D.P., et al. Isolation of two novel metalloproteinase-disintegrin (ADAM) cDNAs that show testis-specific gene expression.

PMID: 27333034 by Letronne F., et al. ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease.