ABCA12 Antibodies

AND ABCA12 ELISA kits, ABCA12 Proteins

Many biological assays use antibodies to detect ABCA12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCA12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCA12 antibodies...

We validate the specificity of these antibodies to ABCA12 by testing them on tissues known to express ABCA12 positively and negatively. Browse below to find the ABCA12 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABCA12 Infographic by Boster Bio

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Anti-ABCAC ABCA12 Antibody

Human

IHC

$380
Cat # A03728
100ul

ABCA12 Overview

Facts about ATP-binding cassette sub-family A member 12.

ABCA12 3D structure. Source: alphafold

ATP-binding cassette sub-family A member 12 (ABCA12)

Probable transporter involved in lipid homeostasis. .

Gene Information

Human
Gene Name:	ABCA12
Uniprot:	Q86UK0
Entrez:	26154

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ABC12; ATP-binding cassette 12; ATP-binding cassette transporter 12; ATP-binding cassette, sub-family A (ABC1), member 12; DKFZP434G232; EC 3.6.3; EC 3.6.3.25; FLJ41584; ichthyosis congenita II, lamellar ichthyosis B; ICR2B; LI2ATP-binding cassette sub-family A member 12

Molecular Weight

Mass (kDA):
293.237 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (214931542..215138626, complement)

Tissue Specificity

Mainly expressed in the stomach, placenta, testis and fetal brain.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Ichthyoses
Congenital Nonbullous Ichthyosiform Erythroderma
Harlequin Fetus
Dermatologic Disorders
Congenital Ichthyosis
Exfoliative Dermatitis
Ichthyosiform Erythroderma, Congenital
Hyperkeratosis
Malignant Neoplasms
Neoplasms
Infective Disorder
Malignant Paraganglionic Neoplasm

Ectropion
Atherosclerosis
Alzheimer's Disease
Abnormal Degeneration
Hereditary Diseases
Tangier Disease
Oligohydramnios

Interacting Proteins

ABCA1

Pathways

Transport
Lipid Transport
Keratinocyte Differentiation
Secretion
Keratinization
Lipid Homeostasis
Pathogenesis
Localization
Drug Resistance
Cholesterol Efflux
Cholesterol Transport
Transmembrane Transport

Cornification
Sterol Transport
Regulation Of Intestinal Cholesterol Absorption
Immune Response
Skin Development
Exocytosis
Intestinal Cholesterol Absorption

PTMs

Phosphorylation

Research Areas

ABC Transporters
Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCA12

References

PMID: 12697999 by Annilo T., et al. Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34.

PMID: 20672373 by Akiyama M.; ABCA12 mutations and autosomal recessive congenital ichthyosis: a review of genotype/phenotype correlations and of pathogenetic concepts.