ADAP1 Antibodies

AND ADAP1 ELISA kits, ADAP1 Proteins

Many biological assays use antibodies to detect ADAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAP1 antibodies...

We validate the specificity of these antibodies to ADAP1 by testing them on tissues known to express ADAP1 positively and negatively. Browse below to find the ADAP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADAP1 Infographic by Boster Bio

All ADAP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ADAP1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A07298
100ul

Centaurin alpha 1 (ADAP1) (NM_006869) Human Recombinant Protein

$813
Cat # PROTO75689
20 µg

Centaurin alpha 1 (ADAP1) (NM_006869) Human Over-expression Lysate

Human

$628
Cat # LS011033
100 µg

ADAP1 Overview

Facts about Arf-GAP with dual PH domain-containing protein 1.

ADAP1 3D structure. Source: alphafold

Arf-GAP with dual PH domain-containing protein 1 (ADAP1)

GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).

Gene Information

Human
Gene Name:	ADAP1
Uniprot:	O75689
Entrez:	11033

Family

Belongs to:

No superfamily

Alternative Names

arf-GAP with dual PH domain-containing protein 1; ArfGAP with dual PH domains 1; CENTA1centaurin-alpha-1; centaurin, alpha 1; centaurin-alpha; Centaurin-alpha-1; cnt-a1; GCS1L; p42IP4; Putative MAPK-activating protein PM25

Molecular Weight

Mass (kDA):
43.395 kDA

Genomic Context


Human

Location:	7p22.3
Sequence:	7; NC_000007.14 (897900..955407, complement)

Tissue Specificity

Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.

Subcellular Localizations

Nucleus. Cytoplasm. Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.

Diseases

Neuroblastoma
Alzheimer's Disease
Senile Plaques
Nervousness
Chimera Disorder
Tissue Adhesions

Plaque, Amyloid

Interacting Proteins

DVL3
GOLGA2
KIF13B
SDCBP2

Pathways

Localization
Transport
Actin Cytoskeleton Organization
Cytoskeleton Organization
Programmed Cell Death
Cell Cycle
Cell Death
Cellular Localization

Lipid Binding
Membrane Docking
Myelination

PTMs

Ribosylation

Phosphorylation

Cleavage

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAP1

References

PMID: 10448098 by Venkateswarlu K., et al. Molecular cloning and functional characterization of a human homologue of centaurin-alpha.

PMID: 10333475 by Venkateswarlu K., et al. Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.