Product Info Summary
SKU: | A06741 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-AMOTL1/Angiomotin Like 1 Antibody
View all Angiomotin like 1 Antibodies
SKU/Catalog Number
A06741
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-AMOTL1/Angiomotin Like 1 Antibody (Catalog # A06741). Tested in IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-AMOTL1/Angiomotin Like 1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06741)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human AMOTL1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06741 is reactive to AMOTL1 in Human, Mouse
Reconstitution
Calculated molecular weight
106574 MW
Background of Angiomotin like 1
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Bratt A., Gene 298:69-77(2002).
Bratt A., Gene 310:231-231(2003).
Yu L.-R., J. Proteome Res. 6:4150-4162(2007).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06741 is guaranteed for IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using AMOTL1 antibody A06741.
Protein Target Info & Infographic
Gene/Protein Information For AMOTL1 (Source: Uniprot.org, NCBI)
Gene Name
AMOTL1
Full Name
Angiomotin-like protein 1
Weight
106574 MW
Superfamily
angiomotin family
Alternative Names
Angiomotin-like protein 1;AMOTL1; Amotl1|2310010G08Rik, 2310067L22Rik, 4932416D09Rik, JE, JEAP, mFLJ00155|angiomotin-like 1|angiomotin-like protein 1|junction-enriched and -associated protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AMOTL1, check out the AMOTL1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AMOTL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AMOTL1/Angiomotin Like 1 Antibody (A06741)
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No publications found for A06741
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Customer Q&As
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4 Customer Q&As for Anti-AMOTL1/Angiomotin Like 1 Antibody
Question
Please see the WB image, lot number and protocol we used for skeletal muscle testis using anti-AMOTL1/Angiomotin Like 1 antibody A06741. Please let me know if you require anything else.
V. Rodriguez
Verified customer
Asked: 2017-09-06
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2017-09-06
Question
Does anti-AMOTL1/Angiomotin Like 1 antibody A06741 work on horse IHC with cervix carcinoma?
N. Edwards
Verified customer
Asked: 2016-10-10
Answer
Our lab technicians have not validated anti-AMOTL1/Angiomotin Like 1 antibody A06741 on horse. You can run a BLAST between horse and the immunogen sequence of anti-AMOTL1/Angiomotin Like 1 antibody A06741 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated horse samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in horse cervix carcinoma in IHC, you can get your next antibody for free.
Boster Scientific Support
Answered: 2016-10-10
Question
We are currently using anti-AMOTL1/Angiomotin Like 1 antibody A06741 for human tissue, and we are satisfied with the IHC results. The species of reactivity given in the datasheet says human, mouse. Is it possible that the antibody can work on horse tissues as well?
R. Zhao
Verified customer
Asked: 2014-11-21
Answer
The anti-AMOTL1/Angiomotin Like 1 antibody (A06741) has not been validated for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2014-11-21
Question
Is this A06741 anti-AMOTL1/Angiomotin Like 1 antibody reactive to the isotypes of AMOTL1?
D. Huang
Verified customer
Asked: 2013-04-05
Answer
The immunogen of A06741 anti-AMOTL1/Angiomotin Like 1 antibody is Synthesized peptide derived from internal of human AMOTL1. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2013-04-05