ARHGAP6 Antibodies

AND ARHGAP6 ELISA kits, ARHGAP6 Proteins

Many biological assays use antibodies to detect ARHGAP6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARHGAP6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARHGAP6 antibodies...

We validate the specificity of these antibodies to ARHGAP6 by testing them on tissues known to express ARHGAP6 positively and negatively. Browse below to find the ARHGAP6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARHGAP6 Infographic by Boster Bio

All ARHGAP6 Products

Product

Figures

Specificity

Applications

Price

Anti-RHG06 ARHGAP6 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A10953
100ul

ARHGAP6 (NM_013423) Human Recombinant Protein

$1249
Cat # PROTO43182
20 µg

ARHGAP6 (NM_013423) Human Over-expression Lysate

Human

$960
Cat # LS000395
100 µg

ARHGAP6 Overview

Facts about Rho GTPase-activating protein 6.

ARHGAP6 3D structure. Source: alphafold

Rho GTPase-activating protein 6 (ARHGAP6)

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton.

Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body altering the cell morphology. .

Gene Information

Human
Gene Name:	ARHGAP6
Uniprot:	O43182
Entrez:	395

Family

Belongs to:

No superfamily

Alternative Names

Rho GTPase activating protein 6; rho GTPase-activating protein 6; RHOGAP6; rhoGAPX-1; Rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1

Molecular Weight

Mass (kDA):
105.947 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (11137544..11665920, complement)

Tissue Specificity

Highly expressed in kidney, heart and skeletal muscle followed by retina, lymphoblast, placenta, lung, brain, pancreas and liver.

Subcellular Localizations

Cytoplasm.

Diseases

Microphthalmos
Microphthalmia, Syndromic 7
Malignant Neoplasms
Neoplasms
Congenital Absence
Skin Abnormalities
Sex Chromosome Aberrations
Monosomy
Carcinogenesis
Embryonic Mosaic
Malnutrition
Malignant Neoplasm Of Breast

Carcinoma
Dental Fluorosis, Acquired
Chondrosarcoma
Whiplash Injuries
Acidosis
Long Qt Syndrome

Pathways

Amelogenesis
Pathogenesis
Sperm Motility
Acrosome Reaction
Cell Development
Immune Response
Synaptic Transmission

Neurogenesis
Rna Interference

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARHGAP6

References

PMID: 10699171 by Prakash S.K., et al. Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.

PMID: 9417914 by Schaefer L., et al. Cloning and characterization of a novel rho-type GTPase-activating protein gene (ARHGAP6) from the critical region for microphthalmia with linear skin defects.