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- Table of Contents
Facts about Ataxin-2-like protein.
Human | |
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Gene Name: | ATXN2L |
Uniprot: | Q8WWM7 |
Entrez: | 11273 |
Belongs to: |
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ataxin-2 family |
A2DA2RP; A2LG; A2LP; ataxin 2 related protein; ataxin 2-like; Ataxin-2 domain protein; ataxin-2-like protein; Ataxin-2-related protein
Mass (kDA):
113.374 kDA
Human | |
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Location: | 16p11.2 |
Sequence: | 16; NC_000016.10 (28823048..28837237) |
Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells.
Membrane; Peripheral membrane protein. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition of methylation alters nuclear localization (PubMed:25748791). Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791).
PMID: 11784712 by Meunier C.F., et al. Cloning and characterization of a family of proteins associated with Mpl.
PMID: 14769358 by Figueroa K.P., et al. Identification and expression of the gene for human ataxin-2-related protein on chromosome 16.