ABR Antibodies

AND ABR ELISA kits, ABR Proteins

Many biological assays use antibodies to detect ABR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABR antibodies...

We validate the specificity of these antibodies to ABR by testing them on tissues known to express ABR positively and negatively. Browse below to find the ABR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABR Infographic by Boster Bio

All ABR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ABR Antibody Picoband®

3 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9972
100 μg/vial

ABR (NM_021962) Human Over-expression Lysate

Human

$960
Cat # LS000029
100 µg

Anti-ABR Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01719
100 μg/vial

ABR Overview

Facts about Active breakpoint cluster region-related protein.

ABR 3D structure. Source: alphafold

Active breakpoint cluster region-related protein (ABR)

GTPase-activating protein for RAC and CDC42.
Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.

Gene Information

Human
Gene Name:	ABR
Uniprot:	Q12979
Entrez:	29

Family

Belongs to:

No superfamily

Alternative Names

active BCR-related gene; active breakpoint cluster region-related protein; FLJ45954; MDB

Molecular Weight

Mass (kDA):
97.598 kDA

Genomic Context


Human

Location:	17p13.3
Sequence:	17; NC_000017.11 (1003519..1229722, complement)

Tissue Specificity

Highly enriched in the brain. Much weaker expression in heart, lung and muscle.

Subcellular Localizations

Cell projection, dendritic spine. Cell projection, axon. Cell junction, synapse.

Diseases

Sensorineural Hearing Loss (disorder)
Hearing Problem
Complete Hearing Loss
Acoustic Neuroma
Neoplasms
Noise-induced Hearing Loss
Nervousness
Lymphoma, Non-hodgkin
Conductive Hearing Loss
Neuroma
Presbycusis
Auditory Neuropathy

Otitis Media
Neurilemmoma
Hearing Loss, High-frequency
Vertigo
Ear Inflammation
Hearing Loss, Bilateral

Pathways

Reflex
Aging
Pathogenesis
Localization
Cell Death
Transport
Startle Response
Myelination
Regeneration
Prepulse Inhibition
Synaptic Transmission
Secretion
Coagulation

Innervation
Pigmentation
Sulfate Reduction
Lactation
Brain Development
Exocytosis
Echolocation

PTMs

Phosphorylation
Reduction
Cleavage
Nitration
Glycosylation

Oxidation
Methylation
Sulphation
Hydroxylation
Amidation

Research Areas

Angiogenesis
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABR

References

PMID: 8262969 by Tan E.-C., et al. The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins.

PMID: 8349582 by Heisterkamp N., et al. Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain.