Alsin Antibodies

AND ALS2 ELISA kits, Alsin Proteins

Many biological assays use antibodies to detect Alsin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alsin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alsin antibodies...

We validate the specificity of these antibodies to Alsin by testing them on tissues known to express ALS2 positively and negatively. Browse below to find the ALS2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ALS2 Infographic by Boster Bio

All ALS2 Products

Product

Figures

Specificity

Applications

Price

Anti-Alsin ALS2 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A02991
100ul

Anti-Alsin ALS2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02991-1
100ul

ALS2 Overview

Facts about Alsin.

ALS2 3D structure. Source: alphafold

Alsin (ALS2)

May act as a GTPase regulator.
Controls survival and growth of spinal motoneurons (By similarity).

. .

Gene Information

Human
Gene Name:	ALS2
Uniprot:	Q96Q42
Entrez:	57679

Family

Belongs to:

No superfamily

Alternative Names

ALS2CR6; alsin; ALSJ; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6; amyotrophic lateral sclerosis 2 (juvenile); Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein; FLJ31851; IAHSP; KIAA1563; MGC87187; PLSJ

Molecular Weight

Mass (kDA):
183.634 kDA

Genomic Context


Human

Location:	2q33.1
Sequence:	2; NC_000002.12 (201700267..201781153, complement)

Diseases

Sclerosis
Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Spastic Paraplegia, Hereditary
Neurodegenerative Disorders
Paraplegia
Spastic Paraplegia
Nerve Degeneration
Neurotoxicity Syndromes
Atrophy

Weakness
Muscle Weakness
Candidiasis
Deglutition Disorders
Muscle Spasticity
Nervousness

Interacting Proteins

RAB5A

Pathways

Pathogenesis
Transport
Localization
Cell Death
Endocytosis
Neuroprotection
Translation
Biofilm Formation
Macropinocytosis
Microtubule-based Transport
Virulence
Mating
Methylation

Cell Growth
Cell Adhesion
Cell Activation
Aging
Tube Formation
Hypersensitivity
Cell Cycle Arrest

PTMs

Phosphorylation
Cleavage

Methylation
Glycosylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALS2

References

PMID: 11586297 by Yang Y., et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis.

PMID: 11586298 by Hadano S., et al. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.