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- Table of Contents
Facts about Cyclic AMP-dependent transcription factor ATF-3.
It might repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Human | |
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Gene Name: | ATF3 |
Uniprot: | P18847 |
Entrez: | 467 |
Belongs to: |
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bZIP family |
activating transcription factor 3cAMP-dependent transcription factor ATF-3; ATF3deltaZip2; ATF3deltaZip2c; ATF3deltaZip3; cyclic AMP-dependent transcription factor ATF-3
Mass (kDA):
20.576 kDA
Human | |
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Location: | 1q32.3 |
Sequence: | 1; NC_000001.11 (212565334..212620777) |
Nucleus.
PMID: 7515060 by Chen B.P.C., et al. ATF3 and ATF3 delta Zip. Transcriptional repression versus activation by alternatively spliced isoforms.
PMID: 12034827 by Hashimoto Y., et al. An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli.