ACP3 Antibodies

AND ACP3 ELISA kits, ACP3 Proteins

Many biological assays use antibodies to detect ACP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACP3 antibodies...

We validate the specificity of these antibodies to ACP3 by testing them on tissues known to express ACP3 positively and negatively. Browse below to find the ACP3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACP3 Infographic by Boster Bio

All ACP3 Products

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Human Prostatic Acid Phosphatase/ACPP Recombinant Protein

Enzyme Activity, SDS-PAGE

$265
Cat # PROTP15309
Starting from 10ug

Anti-PAP/ACP3 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02082-2
100 μg/vial

ACP3 Overview

Facts about Prostatic acid phosphatase.

ACP3 3D structure. Source: alphafold

Prostatic acid phosphatase (ACP3)

A non-specific tyrosine phosphatase that dephosphorylates a varied variety of substrates under acidic conditions (pH 4-6) such as alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma.

Gene Information

Human
Gene Name:	ACP3
Uniprot:	P15309
Entrez:	55

Family

Belongs to:

histidine acid phosphatase family

Alternative Names

Prostatic acid phosphatase

Molecular Weight

Mass (kDA):
44.566 kDA

Genomic Context


Human

Location:	3q22.1
Sequence:	3; NC_000003.12 (132317403..132368765)

Tissue Specificity

Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer.

Subcellular Localizations

[Isoform 1]: Secreted.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Appears to shuttle between the cell membrane and intracellular vesicles. Colocalizes with FLOT1 at cell membrane and in intracellular vesicles (PubMed:17638863). Colocalizes with LAMP2 on the lysosome membrane (PubMed:17897319).

Interacting Proteins

ERBB2

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACP3

References

PMID: 1375464 by Sharief F.S., et al. Structure of human prostatic acid phosphatase gene.

PMID: 1989985 by van Etten R.L., et al. Covalent structure, disulfide bonding, and identification of reactive surface and active site residues of human prostatic acid phosphatase.