ADCYAP1R1 Antibodies

AND ADCYAP1R1 ELISA kits, ADCYAP1R1 Proteins

Many biological assays use antibodies to detect ADCYAP1R1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADCYAP1R1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADCYAP1R1 antibodies...

We validate the specificity of these antibodies to ADCYAP1R1 by testing them on tissues known to express ADCYAP1R1 positively and negatively. Browse below to find the ADCYAP1R1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADCYAP1R1 Infographic by Boster Bio

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Anti-PACR ADCYAP1R1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A03810
100ul

ADCYAP1R1 Overview

Facts about Pituitary adenylate cyclase-activating polypeptide type I receptor.

ADCYAP1R1 3D structure. Source: alphafold

Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1)

This is a receptor for PACAP-27 and PACAP-38.
The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility.

Gene Information

Human
Gene Name:	ADCYAP1R1
Uniprot:	P41586
Entrez:	117

Family

Belongs to:

G-protein coupled receptor 2 family

Alternative Names

ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC1R; PACAP type I receptor; PACAPR; PACAP-R1; PACAP-R-1; PACAPRI; PACAPRPAC1; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; pituitary adenylate cyclase-activating polypeptide type I receptor

Molecular Weight

Mass (kDA):
53.314 kDA

Genomic Context


Human

Location:	7p14.3
Sequence:	7; NC_000007.14 (31052308..31111479)

Tissue Specificity

Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Pituitary Diseases
Nervousness
Neoplasms
Malignant Neoplasms
Disease Of Adrenal Medulla
Malignant Neoplasm Of Prostate
Carcinoma
Malignant Paraganglionic Neoplasm
Prostatic Neoplasms
Malignant Neoplasm Of Lung
Neuroblastoma
Malignant Neoplasm Of Breast

Pheochromocytoma
Post-traumatic Stress Disorder
Nerve Damage
Malignant Tumor Of Colon
Observation Of Neuromuscular Block
Inflammation

Interacting Proteins

ADCYAP1

Pathways

Secretion
Cell Proliferation
Localization
Neurogenesis
Gastric Acid Secretion
Acid Secretion
Insulin Secretion
Catecholamine Secretion
Spermatogenesis
Pathogenesis
Reverse Transcription
Associative Learning
Reflex

Glucose Homeostasis
Cell Differentiation
Regeneration
Cellular Localization
System Development
Vasodilation
Circadian Rhythm

PTMs

Phosphorylation
Cleavage

Glycosylation
Methylation

Deglycosylation

Research Areas

Cancer
Cell Cycle and Replication
GPCR
Neuroscience
Neurotransmission

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADCYAP1R1

References

PMID: 7902709 by Ogi K., et al. Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor.

PMID: 7851900 by Stoffel M., et al. Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical and genetic map of chromosome 7.