Alpha-adducin Antibodies

AND ADD1 ELISA kits, Alpha-adducin Proteins

Many biological assays use antibodies to detect Alpha-adducin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-adducin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-adducin antibodies...

We validate the specificity of these antibodies to Alpha-adducin by testing them on tissues known to express ADD1 positively and negatively. Browse below to find the ADD1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADD1 Infographic by Boster Bio

All ADD1 Products

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Product

Figures

Specificity

Applications

Price

Anti-ADD1 (Ab-726) Antibody

6 Q&As

Human, Mouse, Rat

IF, IHC, WB

$360
Cat # A01575
100 µl

ADD1/2 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1016
1 kit, containing one 96-well plate and all necessary reagents

ADD1/2 (Phospho-Ser726) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC1935
1 kit, containing two 96-well plates and all necessary reagents

Anti-Adducin Alpha / Beta (phospho-S726/713) ADD1 Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A01575S726
100ul

Anti-Adducin Alpha (phospho-T445) ADD1 Antibody

Human, Mouse, Rat

IHC

$482
Cat # A01575T445
100ul

alpha Adducin (ADD1) (NM_001119) Human Recombinant Protein

$813
Cat # PROTP35611
20 µg

alpha Adducin (ADD1) (NM_001119) Human Over-expression Lysate

Human

$960
Cat # LS000118
100 µg

ADD1 Overview

Facts about Alpha-adducin.

ADD1 3D structure. Source: alphafold

Alpha-adducin (ADD1)

Membrane-cytoskeleton-associated protein that promotes the assembly of this spectrin-actin network. Binds to calmodulin.

Gene Information

Human
Gene Name:	ADD1
Uniprot:	P35611
Entrez:	118

Family

Belongs to:

aldolase class II family

Alternative Names

ADDA; adducin 1 (alpha); alpha-adducin; erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha; MGC3339; MGC44427

Molecular Weight

Mass (kDA):
80.955 kDA

Genomic Context


Human

Location:	4p16.3
Sequence:	4; NC_000004.12 (2843844..2930076)

Tissue Specificity

Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.

Diseases

Hypertensive Disease
Essential Hypertension
Cardiovascular Diseases
Obesity
Cerebrovascular Accident
Diabetes Mellitus
Infarction
Insulin Resistance
Myocardial Infarction
Insulin Sensitivity
Diabetes Mellitus, Non-insulin-dependent
Cholangiocarcinoma
Atherosclerosis

Coronary Artery Disease
Hemorrhage
Huntington Disease
5,10-methylenetetrahydrofolate Reductase Deficiency
Heart Diseases
Ischemic Stroke
Kidney Diseases

Interacting Proteins

HMG20A

Pathways

Transport
Energy Homeostasis
Pathogenesis
Cholesterol Homeostasis
Excretion
Cell Differentiation
Fatty Acid Oxidation
Regulation Of Gene Expression
Tissue Development
Reverse Transcription
Glucose Transport
Cell Proliferation
Adipose Tissue Development

Angiogenesis
Germination
Fat Cell Differentiation
Secretion
Stem Cell Differentiation
Osteoblast Differentiation
Shoot Development

PTMs

Phosphorylation
Oxidation

Cleavage
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADD1

References

PMID: 1840603 by Joshi R.L., et al. Primary structure and domain organization of human alpha and beta adducin.

PMID: 1284592 by Goldberg Y.P., et al. Cloning and mapping of the alpha-adducin gene close to D4S95 and assessment of its relationship to Huntington disease.