APPL2 Antibodies

AND APPL2 ELISA kits, APPL2 Proteins

Many biological assays use antibodies to detect APPL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with APPL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop APPL2 antibodies...

We validate the specificity of these antibodies to APPL2 by testing them on tissues known to express APPL2 positively and negatively. Browse below to find the APPL2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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APPL2 Infographic by Boster Bio

All APPL2 Products

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Product

Figures

Specificity

Applications

Price

Anti-DIP13B (APPL2) Mouse Monoclonal Antibody [Clone ID: OTI1H8]

Human, Mouse, Rat

$523
Cat # M06626
100 µl

DIP13B (APPL2) (NM_018171) Human Over-expression Lysate

Human

$628
Cat # LS055198
100 µg

APPL2 Overview

Facts about DCC-interacting protein 13-beta.

APPL2 3D structure. Source: alphafold

DCC-interacting protein 13-beta (APPL2)

Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.

Gene Information

Human
Gene Name:	APPL2
Uniprot:	Q8NEU8
Entrez:	55198

Family

Belongs to:

No superfamily

Alternative Names

Adapter protein containing PH domain, PTB domain and leucine zipper motif 2; adaptor protein containing PH domain, PTB domain and leucine zipper motif 2; adaptor protein, phosphotyrosine interaction, PH domain and leucine zippercontaining 2; DCC-interacting protein 13-beta; DIP13BDIP13 beta; Dip13-beta; FLJ10659dip13-beta

Molecular Weight

Mass (kDA):
74.493 kDA

Genomic Context


Human

Location:	12q23.3
Sequence:	12; NC_000012.12 (105173297..105236230, complement)

Tissue Specificity

High levels in brain, heart, kidney and skeletal muscle.

Subcellular Localizations

Early endosome membrane; Peripheral membrane protein. Nucleus. Cell membrane. Endosome membrane. Cytoplasm. Cytoplasmic vesicle, phagosome. Cell projection, ruffle. Cell projection, ruffle membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Early endosomal membrane-bound and nuclear (PubMed:15016378). Translocated into the nucleus upon release from endosomal membranes following internalization of EGF (PubMed:15016378). Associates dynamically with cytoplasmic membrane structures that undergo changes in shape, movement, fusion and fission events (PubMed:18034774). PI(4,5)P2 levels