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- Table of Contents
Facts about Coatomer subunit delta.
In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are little GTP-binding proteins; the complex also influences the Golgi structural integrity, in addition to the processing, activity, and endocytic recycling of LDL receptors (By similarity). .
Human | |
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Gene Name: | ARCN1 |
Uniprot: | P48444 |
Entrez: | 372 |
Belongs to: |
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adaptor complexes medium subunit family |
archain 1; archain vesicle transport protein 1; Archain; coatomer delta subunit; coatomer protein complex, subunit delta; coatomer protein delta-COP; coatomer subunit delta; COPD; Delta-coat protein; delta-COP
Mass (kDA):
57.21 kDA
Human | |
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Location: | 11q23.3 |
Sequence: | 11; NC_000011.10 (118572387..118603033) |
Ubiquitously expressed.
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
PMID: 7782067 by Radice P., et al. The human archain gene, ARCN1, has highly conserved homologs in rice and Drosophila.
PMID: 27476655 by Izumi K., et al. ARCN1 mutations cause a recognizable craniofacial syndrome due to copi-mediated transport defects.