AWAT1 Antibodies

AND AWAT1 ELISA kits, AWAT1 Proteins

Many biological assays use antibodies to detect AWAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AWAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AWAT1 antibodies...

We validate the specificity of these antibodies to AWAT1 by testing them on tissues known to express AWAT1 positively and negatively. Browse below to find the AWAT1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AWAT1 Infographic by Boster Bio

All AWAT1 Products

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Anti-DGAT2L3 AWAT1 Antibody

5 Q&As

Human

$399
Cat # A14578
100μl

DGAT2L3 (AWAT1) (NM_001013579) Human Over-expression Lysate

Human

$628
Cat # LS158833
100 µg

AWAT1 Overview

Facts about Acyl-CoA wax alcohol acyltransferase 1.

AWAT1 3D structure. Source: alphafold

Acyl-CoA wax alcohol acyltransferase 1 (AWAT1)

Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in the skin.

Has a preference for arachidyl alcohol in addition to decyl alcohol, demonstrating its relatively poor activity utilizing saturated long chain alcohols (C16, C18, and C20). .

Gene Information

Human
Gene Name:	AWAT1
Uniprot:	Q58HT5
Entrez:	158833

Family

Belongs to:

diacylglycerol acyltransferase family

Alternative Names

acyl-CoA wax alcohol acyltransferase 1; DGA2; DGAT2L3; Diacylglycerol acyltransferase 2; diacyl-glycerol acyltransferase 2; diacylglycerol O-acyltransferase 2-like 3; Diacylglycerol O-acyltransferase 2-like protein 3; EC 2.3.1.75; Long-chain-alcohol O-fatty-acyltransferase 1

Molecular Weight

Mass (kDA):
37.759 kDA

Genomic Context


Human

Location:	Xq13.1
Sequence:	X; NC_000023.11 (70233489..70240661)

Tissue Specificity

Predominantly expressed in skin, where it is limited to the sebaceous gland. Expressed in more mature, centrally located cells just before their rupture and sebum release. Also expressed in all tissues except spleen. Expressed at higher level in thymus, prostate and testis.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Obesity
Atherosclerosis

Pathways

Lipid Binding

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AWAT1

References

PMID: 15671038 by Turkish A.R., et al. Identification of two novel human Acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily.

PMID: 14970677 by Winter A., et al. Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals.