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- Table of Contents
13 Q&As
Facts about ADP-ribosylation factor GTPase-activating protein 1.
Promotes hydrolysis of the ARF1-bound GTP and so, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a necessity for vesicle's combination with target compartment. Probably regulates ARF1-mediated transportation via its interaction with the KDELR proteins and TMED2.
Human | |
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Gene Name: | ARFGAP1 |
Uniprot: | Q8N6T3 |
Entrez: | 55738 |
Belongs to: |
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No superfamily |
ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; ARF1 GAP; ARF1-directed GTPase-activating protein; ARF1GAP; bA261N11.3; FLJ10767; GAP protein; HRIHFB2281; MGC39924
Mass (kDA):
44.668 kDA
Human | |
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Location: | 20q13.33 |
Sequence: | 20; NC_000020.11 (63272785..63289790) |
Cytoplasm. Golgi apparatus. Associates with the Golgi complex.
PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.
PMID: 11780052 by Deloukas P., et al. The DNA sequence and comparative analysis of human chromosome 20.