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- Table of Contents
Facts about Adhesion G-protein coupled receptor G5.
Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical stimulation (vibration ). .
Human | |
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Gene Name: | ADGRG5 |
Uniprot: | Q8IZF4 |
Entrez: | 221188 |
Belongs to: |
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G-protein coupled receptor 2 family |
G protein-coupled receptor 114; G protein-coupled receptor PGR27; GPR114; G-protein coupled receptor PGR27; PGR27; PGR27G-protein coupled receptor 114; probable G-protein coupled receptor 114
Mass (kDA):
59 kDA
Human | |
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Location: | 16q21 |
Sequence: | 16; NC_000016.10 (57529339..57578182) |
Expressed in immune cells. Primarily found in granulocytes. Found in eosinophils.
Cell membrane; Multi-pass membrane protein.
PMID: 12435584 by Fredriksson R., et al. Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.
PMID: 21724806 by Peng Y.M., et al. Specific expression of GPR56 by human cytotoxic lymphocytes.