ABO Antibodies

AND ABO ELISA kits, ABO Proteins

Many biological assays use antibodies to detect ABO, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABO in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABO antibodies...

We validate the specificity of these antibodies to ABO by testing them on tissues known to express ABO positively and negatively. Browse below to find the ABO antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABO Infographic by Boster Bio

All ABO Products

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Product

Figures

Specificity

Applications

Price

Anti-Blood Group Antigen A (CD173) ABO Monoclonal Antibody

1 Q&As

Human

IHC

$486
Cat # M00315
100ug/vial

ABO (NM_020469) Human Recombinant Protein

$813
Cat # PROTP16442
20 µg

Anti-BGAT Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M00315-1
100 μl/vial

ABO Overview

Facts about Histo-blood group ABO system transferase.

ABO 3D structure. Source: alphafold

Histo-blood group ABO system transferase (ABO)

This protein is based on the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H.

A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. .

Gene Information

Human
Gene Name:	ABO
Uniprot:	P16442
Entrez:	28

Family

Belongs to:

glycosyltransferase 6 family

Alternative Names

A transferase; A3GALNT; A3GALT1; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase;transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; B transferase; B(A) alpha-1,3-galactosyltransferase; EC 2.4.1.37; EC 2.4.1.40; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; GTB; Histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group AB

Molecular Weight

Mass (kDA):
40.934 kDA

Genomic Context


Human

Location:	9q34.2
Sequence:	9; NC_000009.12 (133250401..133275201, complement)

Subcellular Localizations

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Diseases

Blood Group Incompatibility
Erythroblastosis, Fetal
Malignant Neoplasms
Hemolytic Disorder
Neoplasms
Hemolysis (disorder)
Anemia
Decreased Immunologic Activity [pe]
Carcinoma
Leukemia
Hyperbilirubinemia
Hemorrhage

Icterus
Graft-vs-host Disease
Neonatal Jaundice
Ulcer
Infective Disorder
Thrombosis
Von Willebrand Disease

Pathways

Pathogenesis
Coagulation
Secretion
Immune Response
Sensitization
Localization
Glycosylation
Mating
Transport
Donor Selection
Aging
Phagocytosis
Excretion

Methylation
Fertilization
Virulence
Complement Activation
Hemostasis
Cell Adhesion
Inflammatory Response

PTMs

Glycosylation
Methylation
Cleavage
Reduction
Oxidation
Biotinylation
Phosphorylation
Hydroxylation

Acetylation
Deglycosylation
Demethylation
Nitration
Sulphation
Carboxylation
Acylation
Gpi Anchoring

Deamidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABO

References

PMID: 2104828 by Yamamoto F., et al. Cloning and characterization of DNA complementary to human UDP- GalNAc: Fuc alpha 1-->2Gal alpha 1-->3GalNAc transferase (histo-blood group A transferase) mRNA.

PMID: 2333095 by Yamamoto F., et al. Molecular genetic basis of the histo-blood group ABO system.