Disease Info Card

Spastic Paraplegia

Information about Spastic Paraplegia: characteristics, related genes and pathways, plus antibodies you can use for research. This page is being enriched constantly, if you see some information you would like this page to include please send your suggestions to us.

Overview of Spastic Paraplegia

Most recent studies have shown that Spastic Paraplegia shares some biological mechanisms with ataxia, atrophy, muscle-spasticity, muscular-atrophy, nerve-degeneration, nervous-system-disorder, nervousness, neurodegenerative-disorders, paraparesis, paraparesis-spastic, paraplegia, peripheral-neuropathy, peroneal-muscular-atrophy-with-pyramidal-features-autosomal-dominant, primary-lateral-sclerosis, sclerosis, spastic-paraplegia-hereditary, weakness.

Among the many pathways, these few ones have gauged particular interests from scientists studying Spastic Paraplegia, and have been seen in publications frequently: Cell Adhesion, Cell Death, Cell Migration, Cognition, Cytokinesis, Endocytosis, Intracellular Transport, Localization, Membrane Fusion, Microtubule Severing, Muscle Atrophy, Myelination, Oxidative Phosphorylation, Pathogenesis, Reflex, Regeneration, Secretion, Secretory Pathway, Translation, Transport

Quite a number of genes have been found to play important roles in Spastic Paraplegia, such as AAAS, ALS2, APP, ATL1, HSP90B2P, HSPD1, KIF5A, L1CAM, PDXP, PLP1, PRDX5, PTHLH, REEP1, RNF6, SPAST, SPG11, SPG21, SPG7, VCAM1. See what Boster has to offer for the research of these genes by clicking the gene name links below and view a more detailed info card/product listing for that gene.

In a later update, we will include information such as current drugs and therapy solutions as well as on-going and past clinical trials for this disease. Plesae stay updated.

Spastic Paraplegia Related Genes

click to see detail information for each gene

AAAS ALS2 APP
ATL1 HSP90B2P HSPD1
KIF5A L1CAM PDXP
PLP1 PRDX5 PTHLH
REEP1 RNF6 SPAST
SPG11 SPG21 SPG7
VCAM1