PDXP Antibodies

AND PDXP ELISA kits, PDXP Proteins

Many biological assays use antibodies to detect PDXP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDXP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDXP antibodies...

We validate the specificity of these antibodies to PDXP by testing them on tissues known to express PDXP positively and negatively. Browse below to find the PDXP antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDXP Infographic by Boster Bio

All PDXP Products

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Applications

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Human PDXP Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ96GD0
Starting from 10ug

Anti-PDXP Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A09629-2
100 µg/vial

PDXP Overview

Facts about Pyridoxal phosphate phosphatase.

PDXP 3D structure. Source: alphafold

Pyridoxal phosphate phosphatase (PDXP)

Protein serine phosphatase which dephosphorylates'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization.

Required for normal progress through mitosis and normal cytokinesis. Doesn't dephosphorylate phospho-threonines in LIMK1.

Gene Information

Human
Gene Name:	PDXP
Uniprot:	Q96GD0
Entrez:	57026

Family

Belongs to:

HAD-like hydrolase superfamily

Alternative Names

chronophin; CIN; dJ37E16.5; EC 3.1.3; EC 3.1.3.74; FLJ32703; PLP phosphatase; PLP; PLPP; pyridoxal (pyridoxine, vitamin B6) phosphatase; pyridoxal phosphate phosphatase

Molecular Weight

Mass (kDA):
31.698 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (37658723..37666932)

Tissue Specificity

Ubiquitously expressed (at protein level) (PubMed:23223568). Highly expressed in all the regions of central nerve system except the spinal cord. Also expressed at high level in liver and testis. In fetus, it is weakly expressed in all organs except brain (PubMed:14522954, PubMed:15580268).

Subcellular Localizations

Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Diffusely distributed throughout the cytosol during pro-metaphase and metaphase. Detected at the dynamic cell poles during telophase. Detected at the cleavage furrow and contractile ring during cytokinesis. Transiently detected at the plasma memb