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- Table of Contents
Facts about Myelin proteolipid protein.
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Human | |
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Gene Name: | PLP1 |
Uniprot: | P60201 |
Entrez: | 5354 |
Belongs to: |
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myelin proteolipid protein family |
DM-20; HLD1; Lipophilin; major myelin proteolipid protein; MMPL; Myelin PLP; myelin proteolipid protein; PLP; PLP/DM20; PLP1; PMD; proteolipid protein 1; spastic paraplegia 2, uncomplicated; SPG2
Mass (kDA):
30.077 kDA
Human | |
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Location: | Xq22.2 |
Sequence: | X; NC_000023.11 (103776506..103792619) |
Cell membrane; Multi-pass membrane protein. Myelin membrane. Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat.
PMID: 3467339 by Diehl H.-J., et al. Individual exons encode the integral membrane domains of human myelin proteolipid protein.
PMID: 2441695 by Simons R., et al. Human myelin DM-20 proteolipid protein deletion defined by cDNA sequence.