Disease Info Card

Limb Defect

Information about Limb Defect: characteristics, related genes and pathways, plus antibodies you can use for research. This page is being enriched constantly, if you see some information you would like this page to include please send your suggestions to us.

Overview of Limb Defect

Most recent studies have shown that Limb Defect shares some biological mechanisms with adams-oliver-syndrome, anus-imperforate, aplasia-nos, atresia, cleft-lip, cleft-palate, congenital-abnormality, congenital-absence, congenital-foot-deformity, congenital-hand-deformities, congenital-heart-defects, dysplasia, growth-retardation, hypoplasia, limb-deformities-congenital, polydactyly, syndactyly, teratogenic-effect.

Among the many pathways, these few ones have gauged particular interests from scientists studying Limb Defect, and have been seen in publications frequently: Bone Development, Cell Death, Cell Differentiation, Cell Division, Cell Growth, Cell Proliferation, Innervation, Keratinization, Limb Development, Limb Morphogenesis, Localization, Ossification, Osteoblast Differentiation, Pathogenesis, Programmed Cell Death, Regeneration, Secretion, Segmentation, Transposition, Vasculogenesis

Quite a number of genes have been found to play important roles in Limb Defect, such as FBXW11, FBXW4, FGF4, FGF8, HOXA13, LRP5, NIPBL, NSDHL, PAEP, RARA, RARB, SALL4, SHH, SS18L1, TBX2, TBX5, TP63, TWIST1. See what Boster has to offer for the research of these genes by clicking the gene name links below and view a more detailed info card/product listing for that gene.

In a later update, we will include information such as current drugs and therapy solutions as well as on-going and past clinical trials for this disease. Plesae stay updated.

Limb Defect Related Genes

click to see detail information for each gene

FBXW11 FBXW4 FGF4
FGF8 HOXA13 LRP5
NIPBL NSDHL PAEP
RARA RARB SALL4
SHH SS18L1 TBX2
TBX5 TP63 TWIST1