TBX2 Antibodies

AND TBX2 ELISA kits, TBX2 Proteins

Many biological assays use antibodies to detect TBX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TBX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TBX2 antibodies...

We validate the specificity of these antibodies to TBX2 by testing them on tissues known to express TBX2 positively and negatively. Browse below to find the TBX2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TBX2 Infographic by Boster Bio

All TBX2 Products

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Product

Figures

Specificity

Applications

Price

TBX2 Colorimetric Cell-Based ELISA

Human, Mouse

ELISA

$480
Cat # EKC1791
1 kit, containing one 96-well plate and all necessary reagents

Anti-TBX2 Antibody

Human, Mouse

ELISA, IHC, WB

$380
Cat # A03437-1
100ul

TBX2 Overview

Facts about T-box transcription factor TBX2.

TBX2 3D structure. Source: alphafold

T-box transcription factor TBX2 (TBX2)

Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.

Acts as a negative regulator of PML function in cellular senescence. Might be required for cardiac atrioventricular canal formation.

Gene Information

Human
Gene Name:	TBX2
Uniprot:	Q13207
Entrez:	6909

Family

Belongs to:

No superfamily

Alternative Names

FLJ10169; T-box 2; T-box protein 2; T-box transcription factor TBX2; TBX2

Molecular Weight

Mass (kDA):
75.066 kDA

Genomic Context


Human

Location:	17q23.2
Sequence:	17; NC_000017.11 (61399843..61409466)

Tissue Specificity

Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Endocardial Cushion Defects
Melanoma
Mammary Neoplasms
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Congenital Heart Defects
Congenital Abnormality
Ulnar-mammary Syndrome Of Pallister
Carcinoma
Carcinogenesis
Neoplasm Metastasis

Tumor Progression
Tissue Adhesions
Malignant Neoplasm Of Pancreas
Hypoplasia
Limb Defect
Growth Retardation
Genomic Instability

Interacting Proteins

Pathways

Senescence
Heart Development
Cell Cycle
Cell Proliferation
Localization
Limb Development
Cellular Senescence
Regionalization
Oncogenesis
Cardiac Conduction
Gastrulation
Cardiac Chamber Formation
Cell Growth

Secretion
Cell Adhesion
Lung Development
Mammary Gland Development
Cell Motility
Eye Development
Gland Development

PTMs

Phosphorylation
Cleavage
Methylation

Sumoylation
Acetylation
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TBX2

References

PMID: 8530034 by Campbell C., et al. Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drosophila omb gene.

PMID: 8597636 by Law D.J., et al. Identification, characterization, and localization to chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family.