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RARB Antibodies
AND RARB ELISA kits, RARB Proteins
Many biological assays use antibodies to detect RARB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RARB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RARB antibodies...
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RARB Infographic by Boster Bio
All RARB Products
Product
Figures
Specificity
Applications
Price
Human
IF, IHC, ICC, WB
$370
Cat # M01912
100 μl
Cat # M01912
100 μl
Human, Mouse
ELISA
$480
Cat # EKC1501
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1501
1 kit, containing one 96-well plate and all necessary reagents
RARB Overview
Facts about Retinoic acid receptor beta.
Retinoic acid receptor beta (RARB)
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers for their goal response elements in response to their ligands, all-trans or 9-cis retinoic acid, and modulate gene expression in various biological processes.
The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression as a result of weak binding to corepressors.
Gene Information
| Human | |
|---|---|
| Gene Name: | RARB |
| Uniprot: | P10826 |
| Entrez: | 5915 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
beta polypeptide; HAP; HBV-activated protein; NR1B2; RAR beta; RARB; retinoic acid receptor, beta; RRB2
Molecular Weight
Mass (kDA):
50.489 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p24.2 |
| Sequence: | 3; NC_000003.12 (24829323..25597932) |
Subcellular Localizations
Nucleus. Cytoplasm.; [Isoform Beta-1]: Nucleus.; [Isoform Beta-2]: Nucleus.; [Isoform Beta-4]: Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Carcinogenesis
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Adenocarcinoma
- Malignant Neoplasm Of Lung
- Malignant Squamous Cell Neoplasm
- Lung Neoplasms
- Prostatic Neoplasms
Interacting Proteins
- MEOX2
- RXRB
- RXRG
Pathways
- Methylation
- Dna Methylation
- Pathogenesis
- Dna Hypermethylation
- Gene Silencing
- Cell Proliferation
- Demethylation
- Secretion
- Transport
- Cell Adhesion
- Immune Response
- Localization
- Dna Hypomethylation
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RARB
bosterbio.com/bosterbio-gene-info-cards/RARB
References
PMID: 2836738 by Benbrook D., et al. A new retinoic acid receptor identified from a hepatocellular carcinoma.
PMID: 2825037 by de The H., et al. A novel steroid thyroid hormone receptor-related gene inappropriately expressed in human hepatocellular carcinoma.