This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about F-box/WD repeat-containing protein 11.
SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1.
Human | |
---|---|
Gene Name: | FBXW11 |
Uniprot: | Q9UKB1 |
Entrez: | 23291 |
Belongs to: |
---|
No superfamily |
beta-transducin repeat-containing protein 2; BTRC2F-box/WD repeat-containing protein 1B; BTRCP2FBW1B; F-box and WD repeat domain containing 11; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box protein Fbw1b; F-box/WD repeat-containing protein 11; Fbw11; FBXW1BFbw1b; Homologous to Slimb protein; Hos; KIAA0696F-box and WD repeats protein beta-TrCP2
Mass (kDA):
62.091 kDA
Human | |
---|---|
Location: | 5q35.1 |
Sequence: | 5; NC_000005.10 (171861549..172009604, complement) |
Cytoplasm. Nucleus.
PMID: 10531035 by Cenciarelli C., et al. Identification of a family of human F-box proteins.
PMID: 10694485 by Koike J., et al. Molecular cloning and genomic structure of the betaTRCP2 gene on chromosome 5q35.1.