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Tumor protein 63 Antibodies
AND TP63 ELISA kits, Tumor protein 63 Proteins
Many biological assays use antibodies to detect Tumor protein 63, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tumor protein 63 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tumor protein 63 antibodies...
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TP63 Infographic by Boster Bio
All TP63 Products
Product
Figures
Specificity
Applications
Price
Anti-p63/TP63 Antibody Picoband®
3 Citations 6 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA2056
100 μg/vial
Cat # PA2056
100 μg/vial
Anti-p63/TP63 Antibody Picoband®
2 Citations 17 Q&As
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9152
100 μg/vial
Cat # PB9152
100 μg/vial
Cow, Human, Mouse, Rat
IHC, WB
$486
Cat # M00167
100ug/vial
Cat # M00167
100ug/vial
Anti-p63 TP63 Rabbit Monoclonal Antibody
1 Citations 5 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00167-1
100 μl
Cat # M00167-1
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1430
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1430
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$540
Cat # EKC2169
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2169
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2634
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2634
1 kit, containing two 96-well plates and all necessary reagents
TP63 Overview
Facts about Tumor protein 63.
Tumor protein 63 (TP63)
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity.
Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
Gene Information
| Human | |
|---|---|
| Gene Name: | TP63 |
| Uniprot: | Q9H3D4 |
| Entrez: | 8626 |
Family
| Belongs to: |
|---|
| p53 family |
Alternative Names
amplified in squamous cell carcinoma; Chronic ulcerative stomatitis protein; CUSP; EEC3; EEC3B(p51B); Keratinocyte transcription factor KET; KET; KETRHS; LMS; OFC8; OFC8SHFM4TP73LNBP; p40; p51; p51tumor protein p53-like; p53CP; p63; p63AIS; p73H; p73L; p73LB(p51A); SHFM4; TP53CP; TP53L; TP63; TP73L; Transformation-related protein 63; tumor protein 63; tumor protein p53-competing protein; tumor protein p63 deltaN isoform delta; tumor protein p63; Tumor protein p73-like
Molecular Weight
Mass (kDA):
76.785 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q28 |
| Sequence: | 3; NC_000003.12 (189596746..189897279) |
Tissue Specificity
Widely expressed, notably in heart, kidney, placenta, prostate, skeletal muscle, testis and thymus, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast, eye and prostate express high levels of DeltaN-type isoforms. Isoform 10 is predominantly expressed in skin squamous cell carcinomas, but not in normal skin tissues.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Malignant Squamous Cell Neoplasm
- Ectodermal Dysplasia
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Adenocarcinoma
- Dysplasia
- Neoplasm Metastasis
- Cleft Lip
- Cleft Palate
- Mammary Neoplasms
Interacting Proteins
- CABLES1
- FUS
- HIPK2
- HNRNPK
- ITCH
- NIPSNAP3A
- PRKCD
- SATB2
- SMAD2
- TP53
Pathways
- Cell Cycle
- Cell Proliferation
- Cell Death
- Pathogenesis
- Cell Cycle Arrest
- Cell Growth
- Localization
- Senescence
- Cell Differentiation
- Keratinocyte Differentiation
- Oncogenesis
- Limb Development
- Wound Healing
PTMs
- Phosphorylation
- Cleavage
- Acetylation
- Sumoylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TP63
bosterbio.com/bosterbio-gene-info-cards/TP63
References
PMID: 9703973 by Senoo M., et al. A second p53-related protein, p73L, with high homology to p73.
PMID: 9799841 by Augustin M., et al. Cloning and chromosomal mapping of the human p53-related KET gene to chromosome 3q27 and its murine homolog Ket to mouse chromosome 16.
3 Publications of Boster Tumor protein 63 Antibodies & ELISA Kits
- PubMed ID: 10.1111/jcmm.15160, Ozone therapy promotes the differentiation of basal keratinocytes via increasing...
- PubMed ID: 32210732, Zhong H,Ren Z,Wang X,Miao K,Ni W,Meng Y,Lu L,Wang C,Liu W,Deng CX,Xu RH,Chen G.S...
- PubMed ID: 31748715, Hu L,Sun Y,Luo J,He X,Ye M,Li G,Zhang Y,Bai J,Zhang D,Chang C.Targeting TR4 nucl...
*More publications can be found for each product on its corresponding product page