FLT1-D7 Vascular Endothelial Growth Factor Receptor-1 D1-7 Mouse Recombinant Protein

Product Name

FLT1-D7 Vascular Endothelial Growth Factor Receptor-1 D1-7 Mouse Recombinant Protein

View all VEGFR1/Flt-1 recombinant proteins

SKU/Catalog Number

PROTP35969

Size

2ug, 10ug, 1mg

Description

Soluble FLT1 Mouse Recombinant fused with the Fc part of human IgG1 produced in baculovirus is disulfide-linked homodimeric , polypeptide containing 965 amino acids. The monomers have a molecular mass of 130 kDa. The soluble receptor protein contains all 7 extracellular domains (Tyr23-Asn757), which contain all the information necessary for high affinity ligand binding.

Storage & Handling

Lyophilized FLT-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FLT1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Cite This Product

FLT1-D7 Vascular Endothelial Growth Factor Receptor-1 D1-7 Mouse Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP35969)

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

FLT1 D1-7 was lyophilized from a concentrated (1 mg/ml) sterile solution containing PBS Buffer.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Reconstitution

It is recommended to reconstitute the lyophilized FLT1 Fc/Chimera in PBS not less than 50µg/ml, which can then be further diluted to other aqueous solutions.

Biological Activity

The activity of sVEGFR-1/Fc was determined by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells.

Reconstitution

It is recommended to reconstitute the lyophilized FLT1 Fc/Chimera in PBS not less than 50µg/ml, which can then be further diluted to other aqueous solutions.

Validation Images & Assay Conditions

Gene/Protein Information For FLT1 (Source: Uniprot.org, NCBI)

Alternative Names

EC 2.7.10; EC 2.7.10.1; FLT; FLT1; Flt-1; Fms-like tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor); FRT; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; Vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1 FLT1 FLT, FLT-1, VEGFR-1, VEGFR1 fms related receptor tyrosine kinase 1 vascular endothelial growth factor receptor 1|fms related tyrosine kinase 1|fms-like tyrosine kinase 1|fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)|tyrosine-protein kinase FRT|tyrosine-protein kinase receptor FLT|vascular permeability factor receptor

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

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