Disease Info Card

Neonatal Cholestasis

Information about Neonatal Cholestasis: characteristics, related genes and pathways, plus antibodies you can use for research. This page is being enriched constantly, if you see some information you would like this page to include please send your suggestions to us.

Overview of Neonatal Cholestasis

Most recent studies have shown that Neonatal Cholestasis shares some biological mechanisms with alagille-syndrome, alpha-1-antitrypsin-deficiency, atresia, biliary-atresia, cholestasis, cholestasis-extrahepatic, cytomegalovirus-infections, fibrosis, hepatitis, hepatomegaly, icterus, inborn-errors-of-metabolism, intrahepatic-cholestasis, jaundice-obstructive, liver-cirrhosis, liver-diseases, liver-failure, neonatal-hepatitis, neonatal-jaundice, progressive-intrahepatic-cholestasis-(disorder).

Among the many pathways, these few ones have gauged particular interests from scientists studying Neonatal Cholestasis, and have been seen in publications frequently: Adaptive Immune Response, Bile Acid Conjugation, Cholesterol Esterification, Coagulation, Excretion, Fibrinolysis, Gluconeogenesis, Immune Response, Innate Immune Response, Intestinal Absorption, Intracellular Transport, Lipid Storage, Membrane Fusion, Pathogenesis, Pigment Accumulation, Response To Virus, Secretion, Transforming Growth Factor Beta1 Production, Transport, Tropism

Quite a number of genes have been found to play important roles in Neonatal Cholestasis, such as ABCB11, ABCB4, ACAT1, ALB, ATP8B1, CYP27A1, F2, GGT1, GGT2, GGTLC1, NPC1, PKHD1, POMC, SERPINA1, SLC17A5, SLC25A13, SLC25A5, SLPI, TNF. See what Boster has to offer for the research of these genes by clicking the gene name links below and view a more detailed info card/product listing for that gene.

In a later update, we will include information such as current drugs and therapy solutions as well as on-going and past clinical trials for this disease. Plesae stay updated.