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Pro-opiomelanocortin Antibodies
AND POMC ELISA kits, Pro-opiomelanocortin Proteins
Many biological assays use antibodies to detect Pro-opiomelanocortin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pro-opiomelanocortin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pro-opiomelanocortin antibodies...
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POMC Infographic by Boster Bio
All POMC Products
Product
Figures
Specificity
Applications
Price
Anti-ACTH (Adrenocorticotrophic Hormone) (N-Terminal) (Pituitary Marker) Monoclonal Antibody
1 Citations 3 Q&As
Human, Mouse, Rat
ELISA, IHC
$486
Cat # M00305
100ug/vial
Cat # M00305
100ug/vial
Anti-POMC Monoclonal Antibody
1 Citations 4 Q&As
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M00305-1
100 μl
Cat # M00305-1
100 μl
Human
IF, IHC, WB
$523
Cat # M00305-2
100 µl
Cat # M00305-2
100 µl
POMC Overview
Facts about Pro-opiomelanocortin.
Pro-opiomelanocortin (POMC)
Corticotropin: Stimulates the adrenal glands to release cortisol. .
Gene Information
| Human | |
|---|---|
| Gene Name: | POMC |
| Uniprot: | P01189 |
| Entrez: | 5443 |
Family
| Belongs to: |
|---|
| POMC family |
Alternative Names
ACTH; adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte-stimulating hormone; alpha-MSH; beta-endorphin; beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; CLIP; corticotropin-like intermediary peptide; corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin gamma; LPH; melanotropin alpha; melanotropin beta; melanotropin gamma; met-enkephalin; MSH; NPP; POC; POMC; pro-ACTH-endorphin; proopiomelanocortin preproprotein; proopiomelanocortin; pro-opiomelanocortin
Molecular Weight
Mass (kDA):
29.424 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p23.3 |
| Sequence: | 2; NC_000002.12 (25160853..25168851, complement) |
Tissue Specificity
ACTH and MSH are produced by the pituitary gland.
Subcellular Localizations
Secreted. Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Diseases
- Pituitary Diseases
- Obesity
- Neoplasms
- Pituitary Neoplasms
- Nervousness
- Hyperphagia
- Adenoma
- Physiological Stress
- Cushing Syndrome
- Diabetes Mellitus
- Inflammation
- Pituitary-dependent Cushing's Disease
Interacting Proteins
- HSF2BP
Pathways
- Secretion
- Energy Homeostasis
- Localization
- Pigmentation
- Secretory Pathway
- Feeding Behavior
- Lactation
- Pathogenesis
- Hormone Secretion
- Transport
- Translation
- Regulated Secretory Pathway
- Cell Proliferation
PTMs
- Cleavage
- Phosphorylation
- Acetylation
- Glycosylation
- Amidation
- Methylation
- Oxidation
- Deacetylation
- Sulphation
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POMC
bosterbio.com/bosterbio-gene-info-cards/POMC
References
PMID: 6274691 by Takahashi H., et al. Isolation and structural organization of the human corticotropin- beta-lipotropin precursor gene.
PMID: 6299668 by Whitfeld P.L., et al. The human pro-opiomelanocortin gene: organization, sequence, and interspersion with repetitive DNA.
2 Publications of Boster Pro-opiomelanocortin Antibodies & ELISA Kits
- PubMed ID: 16355451, Chen L, Wang H, Zhao Z, Zhang Y, Huang G. Am J Chin Med. 2005;33(6):945-55. Effe...
- PubMed ID: 25624795, Huo J, Liu J, Wang J, Zhang Y, Wang C, Yang Y, Sun W, Xu S. Neural Regen Res. 20...
*More publications can be found for each product on its corresponding product page