Sialin Antibodies

AND SLC17A5 ELISA kits, Sialin Proteins

Many biological assays use antibodies to detect Sialin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sialin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sialin antibodies...

We validate the specificity of these antibodies to Sialin by testing them on tissues known to express SLC17A5 positively and negatively. Browse below to find the SLC17A5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: CNNM3

SLC17A5 Infographic by Boster Bio

All SLC17A5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SLC17A5 Antibody Picoband®

Human, Monkey, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A06657-2
100 μg/vial

SLC17A5 Overview

Facts about Sialin.

SLC17A5 3D structure. Source: alphafold

Sialin (SLC17A5)

Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is needed for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles.

Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of adrenal gland acinar cells, mediating the physiological nitrate efflux, 25 percent of the circulating nitrate ions is normally removed and secreted in saliva. .

Gene Information

Human
Gene Name:	SLC17A5
Uniprot:	Q9NRA2
Entrez:	26503

Family

Belongs to:

major facilitator superfamily

Alternative Names

AST; ASTSodium/sialic acid cotransporter; FLJ22227; FLJ23268; ISSD; Membrane glycoprotein HP59; NSD; SD; sialic acid storage disease; Sialin; SIASD; SLC17A5; SLD; SLDSolute carrier family 17 member 5; solute carrier family 17 (anion/sugar transporter), member 5; solute carrier family 17, member 5

Molecular Weight

Mass (kDA):
54.64 kDA

Genomic Context


Human

Location:	6q13
Sequence:	6; NC_000006.12 (73593379..73653992, complement)

Tissue Specificity

Found in fetal lung and small intestine, and at lower level in fetal skin and muscle. In the adult, detected in placenta, kidney and pancreas. Abundant in the endothelial cells of tumors from ovary, colon, breast and lung, but is not detected in endothelial cells from the corresponding normal tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.