Anti-NMDAR2C/GRIN2C Antibody Picoband®

Product Name

Anti-NMDAR2C/GRIN2C Antibody Picoband®

View all NMDAR2C Antibodies

SKU/Catalog Number

PB9374

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-NMDAR2C/GRIN2C Antibody Picoband® catalog # PB9374. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NMDAR2C/GRIN2C Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9374)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9374 is reactive to GRIN2C in Human, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

134 kDa

Calculated molecular weight

134209 MW

Background of NMDAR2C

NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9374 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Rat, Human

Positive Control

WB: Rat Brain Tissue

Validation Images & Assay Conditions

Gene/Protein Information For GRIN2C (Source: Uniprot.org, NCBI)

Alternative Names

Glutamate receptor ionotropic, NMDA 2C;GluN2C;Glutamate [NMDA] receptor subunit epsilon-3;N-methyl D-aspartate receptor subtype 2C;NMDAR2C;NR2C;GRIN2C;NMDAR2C; GRIN2C GluN2C, NMDAR2C, NR2C glutamate ionotropic receptor NMDA type subunit 2C glutamate receptor ionotropic, NMDA 2C|N-methyl D-aspartate receptor subtype 2C|N-methyl-D-aspartate receptor subunit 2C|glutamate [NMDA] receptor subunit epsilon-3|glutamate receptor, ionotropic, N-methyl D-aspartate 2C

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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