Anti-VEGFR2/KDR Monoclonal Antibody

Product Name

Anti-VEGFR2/KDR Monoclonal Antibody

View all VEGFR2/KDR/Flk-1 Antibodies

SKU/Catalog Number

MA1040

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-VEGFR2/KDR Monoclonal Antibody catalog # MA1040. Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-VEGFR2/KDR Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1040)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

KDR-1

Isotype

Mouse IgG1

Immunogen

Recombinant human extracellular domain of VEGFR-2 (KDR).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

MA1040 is reactive to Kdr in Human

Reconstitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Observed Molecular Weight

426 kDa

Calculated molecular weight

150394 MW

Background of VEGFR2/KDR/Flk-1

VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

MA1040 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Frozen Section), 1-2μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For Kdr (Source: Uniprot.org, NCBI)

Alternative Names

Vascular endothelial growth factor receptor 2;VEGFR-2;2.7.10.1;Fetal liver kinase 1;FLK-1;Protein-tyrosine kinase receptor flk-1;CD309;Kdr;Flk1; KDR CD309, FLK1, VEGFR, VEGFR2 kinase insert domain receptor vascular endothelial growth factor receptor 2|fetal liver kinase-1|kinase insert domain receptor (a type III receptor tyrosine kinase)|protein-tyrosine kinase receptor Flk-1|soluble VEGFR2|tyrosine kinase growth factor receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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