Anti-Transcription factor SOX-4 SOX4 Antibody

Product Name

Anti-Transcription factor SOX-4 SOX4 Antibody

View all SOX4 Antibodies

SKU/Catalog Number

A01892

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Transcription factor SOX-4 SOX4 Antibody (Catalog # A01892). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

SOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Transcription factor SOX-4 SOX4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01892)

Host

Rabbit

Contents

SOX4 antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

SOX4 antibody was raised against a 16 amino acid peptide near the amino terminus of human SOX4. The immunogen is located within the first 50 amino acids of SOX4.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

SOX4 antibody is human, mouse and rat reactive.

Reactive Species

A01892 is reactive to SOX4 in Human, Mouse, Rat

Applications

A01892 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

47263 MW

Background of SOX4

SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

SOX4 antibody can be used for detection of SOX4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of SOX4 in human testis tissue lysate with SOX4 antibody at 1 μg/ml.

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Immunohistochemistry of SOX4 in rat testis tissue with SOX4 antibody at 5 μg/mL.

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Immunofluorescence of SOX4 in rat testis tissue with SOX4 antibody at 20 μg/mL.

Gene/Protein Information For SOX4 (Source: Uniprot.org, NCBI)

Alternative Names

ecotropic viral integration site 16; EVI16; SRY (sex determining region Y)-box 4; SRY-related HMG-box gene 4; transcription factor SOX-4 SOX4 CSS10, EVI16 SRY-box transcription factor 4 transcription factor SOX-4|SRY (sex determining region Y)-box 4|SRY-box 4|SRY-related HMG-box gene 4|ecotropic viral integration site 16

For more info on SOX4, check out the SOX4 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SOX4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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