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Key=meta_description, value=Boster Bio Anti-Oncostatin M/OSM Antibody Picoband® catalog # PB9732. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. Supplied as 100μg/vial in Lyophilized form antibody.
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Key=image_label, value=Anti- Oncostatin M Picoband antibody, PB9732, Western blotting
All lanes: Anti Oncostatin M (PB9732) at 0.5ug/ml
Lane 1: A549 Whole Cell Lysate at 40ug
Lane 2: HUT Whole Cell Lysate at 40ug
Lane 3: JURKAT Whole Cell Lysate at 40ug
Lane
Key=small_image_label, value=Anti- Oncostatin M Picoband antibody, PB9732, Western blotting
All lanes: Anti Oncostatin M (PB9732) at 0.5ug/ml
Lane 1: A549 Whole Cell Lysate at 40ug
Lane 2: HUT Whole Cell Lysate at 40ug
Lane 3: JURKAT Whole Cell Lysate at 40ug
Lane
Key=thumbnail_label, value=Anti- Oncostatin M Picoband antibody, PB9732, Western blotting
All lanes: Anti Oncostatin M (PB9732) at 0.5ug/ml
Lane 1: A549 Whole Cell Lysate at 40ug
Lane 2: HUT Whole Cell Lysate at 40ug
Lane 3: JURKAT Whole Cell Lysate at 40ug
Lane
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Key=size, value=100 μg/vial
Key=protein_name, value=Oncostatin-M
Key=gene_full_name, value=Oncostatin-M
Key=uniprot_id, value=P13725
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=ELISA, IHC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity
Key=source_company, value=Boster PB9732
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=28484 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interleukins, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway
Key=clonality, value=Polyclonal
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Key=cj_related_products, value=Kaposi Sarcoma:A03518|EK0577|EK1742|EZ0478|A00804|A00804-1
Key=description, value=Boster Bio Anti-Oncostatin M/OSM Antibody Picoband® catalog # PB9732. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Oncostatin M/OSM Antibody Picoband® catalog # PB9732. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Oncostatin M/OSM Antibody Picoband®
Key=contents, value=Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. It has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.
Key=gene_name, value=OSM
Key=synonyms, value=Oncostatin-M;OSM;OSM;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
ELISA, 0.1-0.5μg/ml, -
Western blot, 0.1-0.5μg/ml, Human

Key=subcellular_localization, value= Secreted.
Key=tissue_specificity, value= Highly expressed in retina. Also expressed in brain, testis, heart and skeletal muscle. Isoform 1 expressed in retina, skeletal muscle, heart, lung, ovary, colon, thyroid gland, leukocytes and fetal brain. Isoform 2 expressed in colon, liver, kidney, thyroid gland and leukocytes. Low levels of all isoforms expressed in a variety of tissues. .
Key=protein_function, value= Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). .
Key=application_notes, value=Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 27104|sc 50294|sc 5488|sc 374040|sc 373734|sc 133229|sc 374039|sc 129|sc 50296|sc 365136|sc 390253
Key=immunogen, value=E. coli-derived human Oncostatin M recombinant protein (Position: A26-R220). Human Oncostatin M shares 47.1% and 47.6% amino acid (aa) sequence identity with mouse and rat Oncostatin M, respectively.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=40 kDa
Key=custom_attribute_2, value=WB: A549 Whole Cell, HUT Whole Cell, JURKAT Whole Cell, SW620 Whole Cell, MCF-7 Whole Cell
IHC: human intestinal cancer tissue
Key=custom_attribute_3, value=PB0772
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Anti-Oncostatin M/OSM Antibody Picoband®

Oncostatin M/OSM antibody

Boster Bio Anti-Oncostatin M/OSM Antibody Picoband® catalog # PB9732. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 1 publication(s).

Product Info Summary

SKU: PB9732
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-Oncostatin M/OSM Antibody Picoband®

View all Oncostatin M/OSM Antibodies

SKU/Catalog Number

PB9732

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Oncostatin M/OSM Antibody Picoband® catalog # PB9732. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Oncostatin M/OSM Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9732)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human Oncostatin M recombinant protein (Position: A26-R220). Human Oncostatin M shares 47.1% and 47.6% amino acid (aa) sequence identity with mouse and rat Oncostatin M, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9732 is reactive to OSM in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

40 kDa

Calculated molecular weight

28484 MW

Background of Oncostatin M/OSM

OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. It has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PB9732 is guaranteed for ELISA, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
ELISA, 0.1-0.5μg/ml, -
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: A549 Whole Cell, HUT Whole Cell, JURKAT Whole Cell, SW620 Whole Cell, MCF-7 Whole Cell
IHC: human intestinal cancer tissue

Validation Images & Assay Conditions

Gene/Protein Information For OSM (Source: Uniprot.org, NCBI)

Gene Name

OSM

Full Name

Oncostatin-M

Weight

28484 MW

Superfamily

LIF/OSM family

Alternative Names

Oncostatin-M;OSM;OSM; OSM oncostatin M oncostatin-M

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on OSM, check out the OSM Infographic

OSM infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for OSM: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9732 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Zhu M, Che Q, Liao Y, Wang H, Wang J, Chen Z, Wang F, Dai C, Wan X. Oncol Rep. 2015 Jul;34(1):129-38. Doi: 10.3892/Or.2015.3951. Epub 2015 May 5. Oncostatin M Activates Stat3 To Promote Endometrial Cancer Invasion And Angiogenesis.

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1 Customer Q&As for Anti-Oncostatin M/OSM Antibody Picoband®

Question

We are currently using anti-Oncostatin M/OSM antibody PB9732 for human tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on bovine tissues as well?

Verified Customer

Verified customer

Asked: 2018-06-07

Answer

The anti-Oncostatin M/OSM antibody (PB9732) has not been validated for cross reactivity specifically with bovine tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-06-07

Order DetailsPrice
PB9732

100μg

$370
PB9732-10ug

10μg sample (liquid)

$99
PB9732-Biotin

100 μg Biotin conjugated

$570
PB9732-Cy3

100 μg Cy3 conjugated

$570
PB9732-Dylight488

100 μg Dylight488 conjugated

$570
PB9732-Dylight550

100 μg Dylight550 conjugated

$570
PB9732-Dylight594

100 μg Dylight594 conjugated

$570
PB9732-FITC

100 μg FITC conjugated

$570
PB9732-HRP

100 μg HRP conjugated

$570
PB9732-APC

100 μg APC conjugated

$670
PB9732-PE

100 μg PE conjugated

$670
PB9732-iFluor647

100 μg iFluor647 conjugated

$670
PB9732-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9732
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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