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Key=meta_description, value=Boster Bio Anti-Oncostatin M/Osm Antibody Picoband® catalog # A00804-1. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. Supplied as 100μg/vial in Lyophilized form antibody.
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Key=image_label, value=Figure 1. Western blot analysis of Oncostatin M using anti-Oncostatin M antibody (A00804-1).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded wit
Key=small_image_label, value=Figure 1. Western blot analysis of Oncostatin M using anti-Oncostatin M antibody (A00804-1).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded wit
Key=thumbnail_label, value=Figure 1. Western blot analysis of Oncostatin M using anti-Oncostatin M antibody (A00804-1).
Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded wit
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Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
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Key=description, value=Boster Bio Anti-Oncostatin M/Osm Antibody Picoband® catalog # A00804-1. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Oncostatin M/Osm Antibody Picoband® catalog # A00804-1. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-Oncostatin M/Osm Antibody Picoband®
Key=contents, value=Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. OSM has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.
Key=gene_name, value=Osm
Key=synonyms, value=Oncostatin-M; OSM; Osm
Key=application_details, value=Western blot, 0.1-0.5μg/ml
ELISA, 0.1-0.5μg/ml

Key=subcellular_localization, value= Secreted.
Key=tissue_specificity, value= Widely expressed. Expressed at higher levels in liver, skin and spleen.
Key=protein_function, value= Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Key=immunogen, value=E. coli-derived rat Oncostatin M recombinant protein (Position: K26-R208).
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=28 kDa
Key=custom_attribute_2, value=WB: rat lung tissue, rat spleen tissue, mouse lung tissue, mouse spleen tissue
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Anti-Oncostatin M/Osm Antibody Picoband®

Oncostatin M/OSM antibody

Boster Bio Anti-Oncostatin M/Osm Antibody Picoband® catalog # A00804-1. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 1 publication(s).

Product Info Summary

SKU: A00804-1
Size: 100 μg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-Oncostatin M/Osm Antibody Picoband®

View all Oncostatin M/OSM Antibodies

SKU/Catalog Number

A00804-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Oncostatin M/Osm Antibody Picoband® catalog # A00804-1. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Oncostatin M/Osm Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00804-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived rat Oncostatin M recombinant protein (Position: K26-R208).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00804-1 is reactive to Osm in Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

28 kDa

Calculated molecular weight

28.484kDa

Background of Oncostatin M/OSM

OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. OSM has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A00804-1 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
ELISA, 0.1-0.5μg/ml

Positive Control

WB: rat lung tissue, rat spleen tissue, mouse lung tissue, mouse spleen tissue

Validation Images & Assay Conditions

Gene/Protein Information For Osm (Source: Uniprot.org, NCBI)

Gene Name

Osm

Full Name

Oncostatin-M

Weight

28.484kDa

Superfamily

LIF/OSM family

Alternative Names

Oncostatin-M; OSM; Osm OSM oncostatin M oncostatin-M

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Osm, check out the Osm Infographic

Osm infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Osm: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00804-1 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Zhu M, Che Q, Liao Y, Wang H, Wang J, Chen Z, Wang F, Dai C, Wan X. Oncol Rep. 2015 Jul;34(1):129-38. Doi: 10.3892/Or.2015.3951. Epub 2015 May 5. Oncostatin M Activates Stat3 To Promote Endometrial Cancer Invasion And Angiogenesis.

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Order DetailsPrice
A00804-1

100μg

$370
A00804-1-10ug

10μg sample (liquid)

$99
A00804-1-Biotin

100 μg Biotin conjugated

$570
A00804-1-Cy3

100 μg Cy3 conjugated

$570
A00804-1-Dylight488

100 μg Dylight488 conjugated

$570
A00804-1-Dylight550

100 μg Dylight550 conjugated

$570
A00804-1-Dylight594

100 μg Dylight594 conjugated

$570
A00804-1-FITC

100 μg FITC conjugated

$570
A00804-1-HRP

100 μg HRP conjugated

$570
A00804-1-APC

100 μg APC conjugated

$670
A00804-1-PE

100 μg PE conjugated

$670
A00804-1-iFluor647

100 μg iFluor647 conjugated

$670
A00804-1-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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