Product Info Summary
SKU: | A03659 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-KCNQ4/Kv7.4 Antibody
SKU/Catalog Number
A03659
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-KCNQ4/Kv7.4 Antibody (Catalog # A03659). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-KCNQ4/Kv7.4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03659)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from C-terminal of human KCNQ4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03659 is reactive to KCNQ4 in Human
Reconstitution
Calculated molecular weight
77101 MW
Background of Kv7.4
Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors.
Kubisch C., Cell 96:437-446(1999).
Gregory S.G., Nature 441:315-321(2006).
Selyanko A.A., J. Physiol. (Lond.) 522:349-355(2000).<
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03659 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from HuvEc cells, using KCNQ4 antibody A03659.
Protein Target Info & Infographic
Gene/Protein Information For KCNQ4 (Source: Uniprot.org, NCBI)
Gene Name
KCNQ4
Full Name
Potassium voltage-gated channel subfamily KQT member 4
Weight
77101 MW
Superfamily
potassium channel family
Alternative Names
Potassium voltage-gated channel subfamily KQT member 4;KQT-like 4;Potassium channel subunit alpha KvLQT4;Voltage-gated potassium channel subunit Kv7.4;KCNQ4; KCNQ4 DFNA2, DFNA2A, KV7.4 potassium voltage-gated channel subfamily Q member 4 potassium voltage-gated channel subfamily KQT member 4|potassium channel KQT-like 4|potassium channel subunit alpha KvLQT4|potassium channel, voltage gated KQT-like subfamily Q, member 4|potassium voltage-gated channel, KQT-like subfamily, member 4
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on KCNQ4, check out the KCNQ4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for KCNQ4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-KCNQ4/Kv7.4 Antibody (A03659)
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No publications found for A03659
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