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Key=sku, value=M02902-1
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Key=created_at, value=2021-03-12 20:07:46
Key=updated_at, value=2024-10-31 05:02:01
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Key=name, value=Anti-ITGA3 Antibody (N-term)
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Key=meta_title, value=Anti-ITGA3 Antibody (N-term) | Boster
Key=meta_description, value=Boster Bio Anti-ITGA3 Antibody (N-term) (Catalog # M02902-1). Tested in WB application(s). This antibody reacts with Human.
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Key=url_key, value=anti-itga3-antibody-n-term-m02902-1-boster
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Key=image_label, value=Western blot analysis of lysates from NCI-H292, A549, HepG2 cell line (from left to right), using ALDH2 Antibody(Cat. #M00546-4). M00546-4 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary anti
Key=small_image_label, value=Western blot analysis of lysates from NCI-H292, A549, HepG2 cell line (from left to right), using ALDH2 Antibody(Cat. #M00546-4). M00546-4 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary anti
Key=thumbnail_label, value=Western blot analysis of lysates from NCI-H292, A549, HepG2 cell line (from left to right), using ALDH2 Antibody(Cat. #M00546-4). M00546-4 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary anti
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Key=size, value=80 µl
Key=uniprot_id, value=P26006
Key=applications, value=WB
Key=reactivity, value=Human
Key=predicted_reactivity, value=Bovine, Chicken, Horse, Monkey, Pig, Sheep, Xenopus
Key=source_company, value=Abcepta AP21352a-ev: 75| AP21352a: 192.5
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=116612 Da
Key=product_category, value=Primary Antibodies
Key=research_category, value=Neuroscience
Key=clonality, value=Polyclonal
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Key=cj_related_products, value=Keratinocyte Migration:PA2038|EK1586|A02789|EZ0903^Response To Stimulus:A10017^Skin Development:M04444
Key=description, value=Boster Bio Anti-ITGA3 Antibody (N-term) (Catalog # M02902-1). Tested in WB application(s). This antibody reacts with Human.
Key=short_description, value=Boster Bio Anti-ITGA3 Antibody (N-term) (Catalog # M02902-1). Tested in WB application(s). This antibody reacts with Human.
Key=meta_keyword, value=Anti-ITGA3 Antibody (N-term)
Key=contents, value=Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Key=background, value= Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Key=gene_name, value=ITGA3
Key=synonyms, value=Integrin alpha-3, CD49 antigen-like family member C, FRP-2, Galactoprotein B3, GAPB3, VLA-3 subunit alpha, CD49c, Integrin alpha-3 heavy chain, Integrin alpha-3 light chain, ITGA3, MSK18
Key=application_details, value=WB: 1:2000
Key=subcellular_localization, value=Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid- anchor. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner.
Key=tissue_specificity, value=Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells.
Key=protein_function, value=Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha- 3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Key=application_notes, value=Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=immunogen, value=This ITGA3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.
Key=purification, value=This antibody is purified through a protein A column, followed by peptide affinity purification.
Key=storage, value=Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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