Anti-Kallikrein 1/KLK1 Antibody Picoband®

Product Name

Anti-Kallikrein 1/KLK1 Antibody Picoband®

View all Kallikrein 1 Antibodies

SKU/Catalog Number

PA2038

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Kallikrein 1/KLK1 Antibody catalog # PA2038. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Kallikrein 1/KLK1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2038)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived mouse KLK1 recombinant protein (Position: I25-D261).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2038 is reactive to Klk1 in Mouse

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

29 kDa

Calculated molecular weight

28775 MW

Background of Kallikrein 1

KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2038 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Mouse

Positive Control

WB: Mouse Testis Tissue
IHC: Mouse Kidney Tissue

Validation Images & Assay Conditions

Gene/Protein Information For Klk1 (Source: Uniprot.org, NCBI)

Alternative Names

Kallikrein-1;3.4.21.35;Glandular kallikrein K1;KAL-B;Renal kallikrein;Tissue kallikrein-6;mGK-6;Klk1;Klk-6, Klk6; KLK1 KLKR, Klk6, hK1 kallikrein 1 kallikrein-1|glandular kallikrein 1|kallikrein 1, renal/pancreas/salivary|kallikrein serine protease 1|kidney/pancreas/salivary gland kallikrein|tissue kallikrein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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