Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody

Product Name

Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody

View all ITGA3 Antibodies

SKU/Catalog Number

M02902

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody (Catalog# M02902). Tested in Flow Cytometry, IP, WB, IHC-F application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD49c Purified ITGA3 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02902)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

ASC-1

Isotype

Mouse IgG1 kappa

Immunogen

Human SSC-9 cell line (squamous cell carcinoma). The mouse monoclonal antibody ASC-1 recognizes an extracellular epitope of CD49c (integrin alpha 3), a transmembrane glycoprotein composed of disulfide linked 125 kDa and 30 kDa chains, and expressed on adherent cell lines and to a lesser extent on T and B cells and monocytes.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody does not cross-react with Thy-1.1 alloantigen.

Reactive Species

M02902 is reactive to ITGA3 in Human

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

116612 MW

Background of ITGA3

CD49c / Integrin alpha 3 is a type I transmembrane glycoprotein proteolytically cleaved into two disulfide linked chains. It noncovalently associates with CD29 (integrin beta 1) to form the VLA-3 complex, an adhesion receptor for extracellular matrix components (fibronectin, laminin 1, laminin 5, entactin, and collagen). It is expressed on adherent cells, mainly on fibroblasts, epithelial cells and endothelial cells.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M02902 is guaranteed for Flow Cytometry, IP, IHC-F, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 1-4 μg/ml.

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For ITGA3 (Source: Uniprot.org, NCBI)

Alternative Names

ITGA3, VLA-3 alpha, FRP-2, FRP2, GAPB3 ITGA3 CD49C, FRP-2, GAP-B3, GAPB3, ILNEB, MSK18, VCA-2, VL3A, VLA3a integrin subunit alpha 3 integrin alpha-3|CD49 -like family member C|alpha 3 subunit of VLA-3 receptor| CD49C| by J143|galactoprotein B3|integrin alpha 3|integrin, alpha 3 ( CD49C, alpha 3 subunit of VLA-3 receptor)|testicular tissue protein Li 96|testicular tissue protein Li 98|very late activation protein 3 receptor, alpha-3 subunit

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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