Anti-Integrin alpha 3/ITGA3 Antibody Picoband®

ITGA3 antibody

Boster Bio Anti-Integrin alpha 3/ITGA3 Antibody catalog # PA1621. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 1 publication(s).

Product Info Summary

SKU: PA1621
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: Flow Cytometry, IF, IHC, ICC, WB

Product Name

Anti-Integrin alpha 3/ITGA3 Antibody Picoband®

View all ITGA3 Antibodies

SKU/Catalog Number

PA1621

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Integrin alpha 3/ITGA3 Antibody catalog # PA1621. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Integrin alpha 3/ITGA3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1621)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3, identical to the related rat and mouse sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1621 is reactive to ITGA3 in Human, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

155 kDa

Calculated molecular weight

116612 MW

Background of ITGA3

ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1621 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human, By Heat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human

Positive Control

WB: human U87 whole cell, human A431 whole cell, human A549 whole cell, human U2OS whole cell, rat C6 whole cell, rat PC-12 whole cell
IHC: human lung cancer tissue, human colorectal adenocarcinoma tissue
ICC/IF: A431 cell
FCM: U87 cell

Validation Images & Assay Conditions

Gene/Protein Information For ITGA3 (Source: Uniprot.org, NCBI)

Gene Name

ITGA3

Full Name

Integrin alpha-3

Weight

116612 MW

Superfamily

integrin alpha chain family

Alternative Names

Integrin alpha-3;CD49 antigen-like family member C;FRP-2;Galactoprotein B3;GAPB3;VLA-3 subunit alpha;CD49c;Integrin alpha-3 heavy chain;Integrin alpha-3 light chain;ITGA3;MSK18; ITGA3 CD49C, FRP-2, GAP-B3, GAPB3, ILNEB, MSK18, VCA-2, VL3A, VLA3a integrin subunit alpha 3 integrin alpha-3|CD49 -like family member C|alpha 3 subunit of VLA-3 receptor| CD49C| by J143|galactoprotein B3|integrin alpha 3|integrin, alpha 3 ( CD49C, alpha 3 subunit of VLA-3 receptor)|testicular tissue protein Li 96|testicular tissue protein Li 98|very late activation protein 3 receptor, alpha-3 subunit

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ITGA3, check out the ITGA3 Infographic

ITGA3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ITGA3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1621 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Li H,Yuan L,Long Y,Fang H,Li M,Liu Q,Xia X,Qin C,Zhang Y,Lan X,Gai Y.Synthesis and Preclinical Evaluation of a 68Ga-Radiolabeled Peptide Targeting Very Late Antigen-3 for PET Imaging of Pancreatic Cancer.Mol Pharm.2020 Aug 3;17(8):3000-3008.doi:10.1021/ac
Species: Human, Mouse
PA1621 usage in article: APP, WB, SAMPLE:SW1990,BXPC-3 AND PANC-1 CELLS, DILUTION:1:3000

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1 Customer Q&As for Anti-Integrin alpha 3/ITGA3 Antibody Picoband®

Question

For BP1621,Integrin alpha 3 peptide for PA1621, we have the following questions. 1. Could you please provide the sequence of the protein? Is it a short peptide, a long peptide, or a cyclic peptide? Or roughly how many amino acids? 2. Can this protein be bridged with other materials, such as PEG? Is there any relevant data or literature reference?

Verified customer

Asked: 2022-12-13

Answer

1. The sequence of the immunogen is LFGYSVALHRQTERQQR. 2. Our lab hasn't bridged this peptide with other materials. We are uncertain if it can be be bridged with other materials, such as PEG. We haven't got any relevant data or literature reference to provide.

Boster Scientific Support

Answered: 2022-12-13

Order DetailsPrice
PA1621

100μg

$370
PA1621-10ug

10μg sample (liquid)

$99
PA1621-Biotin

100 μg Biotin conjugated

$570
PA1621-Cy3

100 μg Cy3 conjugated

$570
PA1621-Dylight488

100 μg Dylight488 conjugated

$570
PA1621-Dylight550

100 μg Dylight550 conjugated

$570
PA1621-Dylight594

100 μg Dylight594 conjugated

$570
PA1621-FITC

100 μg FITC conjugated

$570
PA1621-HRP

100 μg HRP conjugated

$570
PA1621-APC

100 μg APC conjugated

$670
PA1621-PE

100 μg PE conjugated

$670
PA1621-iFluor647

100 μg iFluor647 conjugated

$670
PA1621-carrier-free

Carrier Free

$370

More conjugates/formats

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PA1621
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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