Key=store_id
Key=entity_id, value=77059
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=M08081
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2020-03-11 06:18:52
Key=updated_at, value=2024-10-22 05:01:26
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Hu CD112 Purified NECTIN2 Monoclonal Antibody
Key=cj_search_index
Key=publication_count, value=0
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Mouse
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1369
Key=yoast_content_score, value=90
Key=price, value=299.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Hu CD112 Purified NECTIN2 Monoclonal Antibody
Key=meta_description, value=Boster Bio Anti-Hu CD112 Purified NECTIN2 Monoclonal Antibody (Catalog# M08081). Tested in Flow Cytometry, IP, IHC-F application(s). This antibody reacts with Human. Supplied as 0.1 mg in Liquid form antibody.
Key=image, value=/antibody/A01497-apolipoprotein-c-ii_antibody_1_ihc_4x3.jpg
Key=small_image, value=/antibody/A01497-apolipoprotein-c-ii_antibody_1_ihc_4x3.jpg
Key=thumbnail, value=/antibody/A01497-apolipoprotein-c-ii_antibody_1_ihc_4x3.jpg
Key=url_key, value=anti-hu-cd112-purified-nectin2-monoclonal-antibody-m08081-boster
Key=url_path, value=anti-apolipoprotein-c-ii-antibody-a01497-boster
Key=options_container, value=Block after Info Column
Key=image_label, value=Apolipoprotein C-II was detected in paraffin-embedded sections of kidney tissues using goat anti-Apolipoprotein C-II polyclonal antibody (Catalog # A01497) at 5 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1023).
Key=small_image_label, value=Apolipoprotein C-II was detected in paraffin-embedded sections of kidney tissues using goat anti-Apolipoprotein C-II polyclonal antibody (Catalog # A01497) at 5 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1023).
Key=thumbnail_label, value=Apolipoprotein C-II was detected in paraffin-embedded sections of kidney tissues using goat anti-Apolipoprotein C-II polyclonal antibody (Catalog # A01497) at 5 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1023).
Key=msrp_display_actual_price_type, value=Use config
Key=gift_message_available, value=No
Key=size, value=0.1 mg
Key=protein_name, value=Nectin-2
Key=gene_full_name, value=Nectin cell adhesion molecule 2
Key=uniprot_id, value=Q92692
Key=applications, value=Flow Cytometry, IP, IHC-F
Key=reactivity, value=Human
Key=form, value=Liquid
Key=concentration, value=1 mg/ml
Key=cross_reactivity, value=As in case with other anti-CD170 antibodies, this antibody cross-reacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.
Key=clone_number, value=R2.525
Key=predicted_reactivity, value=Primate
Key=source_company, value=Exbio 11-777-C100; Cost: 93.8
Key=isotype, value=Mouse IgG1 kappa
Key=molecular_weight, value=57742 MW
Key=sample_size_available, value=25ug for $99, contact us for details
Key=related_product_skus, value=EK1456,M00717,PA1247,PB9844,PB9845,PB9916,PROTP02647,PROTP02647-1,PROTP02647-2,PROTP02647-3,PROTQ00623
Key=product_category, value=Primary Antibodies, Monoclonal Antibodies
Key=research_category, value=Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Heart Disease, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Pathways and Processes, Signal Transduction
Key=clonality, value=Monoclonal
Key=swatch_image, value=/e/k/ek0396.png
Key=rating_value, value=100
Key=review_count, value=6
Key=phospho_site, value=Phosphorylated, Thr449
Key=mp_exclude_sitemap, value=No
Key=yoast_facebook_image, value=/a/1/a17130-cisd3-primary-antibodies-wb-testing-1.jpg
Key=yoast_twitter_image, value=/a/1/a17130-cisd3-primary-antibodies-wb-testing-1.jpg
Key=cj_related_products, value=Peripheral T-cell Lymphoma:EK1960|A01385-2|EK0740^Regulation Of Cyclin-dependent Protein Kinase Activity:EK1960|A08081-2|A08081-1
Key=description, value=Boster Bio Anti-Hu CD112 Purified NECTIN2 Monoclonal Antibody (Catalog# M08081). Tested in Flow Cytometry, IP, IHC-F application(s). This antibody reacts with Human.
Key=short_description, value=Boster Bio Anti-Hu CD112 Purified NECTIN2 Monoclonal Antibody (Catalog# M08081). Tested in Flow Cytometry, IP, IHC-F application(s). This antibody reacts with Human.
Key=meta_keyword, value=Anti-Hu CD112 Purified NECTIN2 Monoclonal Antibody
Key=contents, value=Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Key=background, value=CD112, also known as nectin-2, is a transmembrane glycoprotein involved in organization of adherens junctions. It also serves as a target molecule for entry of certain strains of herpes simplex virus (HSV) and pseudorabies virus (PRV). It is homologous to CD155, which serves as a target molecule for polio virus. CD112 seems to play a role in neural tube formation, with N-cadherin. Inside the cell, CD112 is connected with actin cytoskeleton through afadin. Variations in the CD112 gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Key=gene_name, value=NECTIN2
Key=synonyms, value=NECTIN2, HVEB, PRR2, PVRL2, PVRR2
Key=application_details, value=Flow cytometry: 1-4 μg/ml.
Key=subcellular_localization, value=Cell membrane; Single-pass type I membrane protein.
Key=tissue_specificity, value=Ubiquitous.
Key=protein_function, value=Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005).
Key=application_notes, value=Anti-apoLipoprotein antibodies have been tested in immunohistochemistry and used for indirect trapping ELISA for quantitation of antigen in serum using a standard curve, immunoprecipitation, immunohistochemistry, and for western blotting for highly sensitive qualitative analysis.
Key=competitor_equivalent_skus, value=sc 19015|sc 19014|sc 19011|sc 368427
Key=immunogen, value=NIH/3T3 cells transfected with human Nectin-2. The mouse monoclonal antibody R2.525 recognizes an extracellular epitope on CD112, a type I transmembrane glycoprotein expressed by myelomonocytic and megakaryocytic cells, and by CD34+ hematopoietic progenitors.
Key=purification, value=Purified by protein-A affinity chromatography.
Key=storage, value=Store at 2-8°C. Do not freeze.
Key=custom_attribute_1, value=42 kDa
Key=options
Key=media_gallery
Key=extension_attributes
Key=tier_price
Key=tier_price_changed
Key=category_ids
Key=is_salable
Key=website_ids
Key=request_path
Key=rating_summary
Key=_cache_instance_store_filter
Key=media_gallery_images