Key=subcellular_localization, value=Cell membrane; Single-pass type I membrane
protein.
Key=tissue_specificity, value=Ubiquitous.
Key=protein_function, value=Modulator of T-cell signaling. Can be either a
costimulator of T-cell function, or a coinhibitor, depending on
the receptor it binds to. Upon binding to CD226, stimulates T-cell
proliferation and cytokine production, including that of IL2, IL5,
IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell
proliferation. These interactions are competitive
(PubMed:26755705). Probable cell adhesion protein
(PubMed:9657005). Key=application_notes, value=Anti-ALG6 antibody has been tested in ELISA, western blot, and immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 58kDa in size corresponding to ALG6 protein by Western blotting in the appropriate cell lysate or extract. Key=competitor_equivalent_skus, value=sc 161737|sc 136341 Key=immunogen, value=Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_002847.1). Key=purification, value=The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Key=storage, value=Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. Key=options Key=media_gallery Key=extension_attributes Key=tier_price Key=tier_price_changed Key=category_ids Key=is_salable Key=website_ids Key=request_path Key=rating_summary Key=_cache_instance_store_filter Key=media_gallery_images
Anti-PVRL2 NECTIN2 Antibody
Nectin-2/CD112 antibody
Boster Bio Anti-PVRL2 NECTIN2 Antibody catalog # A08081-1. Tested in WB,IHC applications. This antibody reacts with Human.
Boster Bio Anti-PVRL2 NECTIN2 Antibody catalog # A08081-1. Tested in WB,IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PVRL2 NECTIN2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08081-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_002847.1).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08081-1 is reactive to NECTIN2 in Human
Reconstitution
Calculated molecular weight
57742 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000 IHC: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on NECTIN2, check out the NECTIN2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NECTIN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$405.00
Troubleshooting
Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.