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Product Info Summary
| SKU: | M03913 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | FACS |
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Product info
Product Name
Anti-hCD6 Antibody (Monoclonal, SPV14)
SKU/Catalog Number
M03913
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-hCD6 Antibody (Monoclonal, SPV14) (Catalog# M03913). Tested in FACS application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-hCD6 Antibody (Monoclonal, SPV14) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03913)
Host
Mouse
Contents
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Monoclonal
Clone Number
SPV14
Isotype
IgG2a Kappa
Immunogen
CD8+ cytotoxic T-cells
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M03913 is reactive to CD6 in Human
Reconstitution
Reconstitute with distilled water.
Observed Molecular Weight
68 kDa
Calculated molecular weight
71801 MW
Background of CD6
This monoclonal antibody recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M03913 is guaranteed for FACS Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FACS: 0.5-1 µg/10^6 cells
Validation Images & Assay Conditions
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Cell Surface flow analysis of hCD6 in PBMC (Lymphocyte gated) using 0.5 &mu
Protein Target Info & Infographic
Gene/Protein Information For CD6 (Source: Uniprot.org, NCBI)
Gene Name
CD6
Full Name
T-cell differentiation antigen CD6
Weight
71801 MW
Alternative Names
T-cell differentiation antigen CD6;T12;TP120;CD6;CD6; CD6 TP120 CD6 molecule T-cell differentiation CD6|CD6 |T12
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD6, check out the CD6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-hCD6 Antibody (Monoclonal, SPV14) (M03913)
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No publications found for M03913
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Customer Q&As
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1 Customer Q&As for Anti-hCD6 Antibody (Monoclonal, SPV14)
Question
We are currently using anti-hCD6 antibody (Monoclonal, SPV14) M03913 for human tissue, and we are happy with the Flow Cytometry results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on dog tissues as well?
M. Lewis
Verified customer
Asked: 2017-10-31
Answer
The anti-hCD6 antibody (Monoclonal, SPV14) (M03913) has not been validated for cross reactivity specifically with dog tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2017-10-31
